[di meliora]

In a research breakthrough:

Researchers from Mount Sinai School of Medicine, have identified the pattern of cell signaling induced by antipsychotic drugs in a complex composed of two brain receptors linked to schizophrenia. The discovery should allow researchers to predict the effectiveness of novel compounds for the treatment of schizophrenia and other serious mental disorders and may accelerate the development of better antipsychotic drugs. The findings are published in the November 23 issue of Cell. http://www.mountsinai.org/about-us/n...sychotic-drugs

Recent studies are in the process of dismantling the chemical imbalance hypothesis as the main culprit causing mental illness, much to the dismay of Big Pharma. So, I expect there will be skeptics who will bemoan the development of "better" antipsychotics.

Albeit, what got me excited is this statement:

"This is a clear example of collaborative, team-based research combining multidisciplinary approaches ranging from cell and molecular biology to computational biophysics, neurochemistry and behavioral pharmacology" said Marta Filizola, PhD, an Associate Professor of Structural and Chemical Biology at Mount Sinai. Dr. Filizola’s team contributed a mechanistic understanding of the glutamate-serotonin signaling triggered by antipsychotic drugs through computer simulations.

In my view, this type of an approach to treatment is long past due. Turf wars and model mongering only impede better methods of treatment. Now if only more would find the will to rein in the inordinate influence and devious machinations of Big Pharma.