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Old Nov 17, 2014, 07:04 AM
Altered Moment's Avatar
Altered Moment Altered Moment is offline
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Member Since: Feb 2014
Location: Michigan
Posts: 5,481
I am primarily interested in this subject because since I was a little kid I have always loved science, biology, chemistry, and physics. I had a chemistry set and microscope when I was 8 years old.

I have major, severe, recurrent, cyclical, treatment resistant depression. In my case I think the dominating factor is genetics and biology. I have had depression for 37 years and have been treating it for 20 years. I have many valid reasons for thinking that in my case it is primarily genetic and biological. I have explained my reasoning many times in these forums and I can elaborate here if you want. I think for many people with mental illness genetics and biology play a role. Not all people. I know there are all kinds of causes for different people. I am just talking about genetics here.

I have never thought that meant I was doomed and it was no use. I just never thought about it that way. I have been aggressively treating it in every which way for twenty years yet I still keep getting them in the same regular patterns. In recent years much worse. For the last nine months I have been doing great because of the meds I am on. I go to therapy and do all the other things I have always done but I could very much tell within two weeks that the Fetzima was working like a miracle. Lifted straight up out of a very severe depression.

Anyway this is just a list of articles I have saved that I have read on the topic if anyone is interested in reading them. There is a growing body of evidence and since the Human Genome Project and the fact that they can sequence a person’s whole genetic code cheap and quick now it is easier to study. Genetically modified mice make things easier to study. I think there will be huge advances in figuring out the human brain in the next ten years.

No particular order-

Stem Cells Reveal How Illness-Linked Genetic Variation Affects Neurons - 08/18/2014

Common Genetic Variation Big Risk Factor for Alcoholism, Mental Illness - Addiction Treatment | Elements | Drug Rehab Treatment Centers

5 Major Mental Illnesses Traced to Same Genetic Variations | Psych Central News

http://www.journalofpsychiatricresea.../abstract?cc=y

NIMH · New Data Reveal Extent of Genetic Overlap Between Major Mental Disorders

http://www.schizophrenia.com/research/hereditygen.htm

GenRED - Major Depression and Genetics - Genetics of Brain Function - Stanford University School of Medicine

Genetic Switch Involved in Depression - NIH Research Matters - National Institutes of Health (NIH)

Depression Research - Psych Central

http://www.nhs.uk/news/2011/05May/Pa...ion-found.aspx

What causes depression? - Harvard Health Publications

New gene for bipolar disorder discovered -- ScienceDaily

Bipolar Disorder, Genetics, and the Brain :: DNA Learning Center

Schizophrenia and Manic-Depressive Disorder: The Biological Roots of Mental ... - Google Books

Cambridge Journals Online - Psychological Medicine - Abstract - Autism as a strongly genetic disorder: evidence from a British twin study

NIMH · Five Major Mental Disorders Share Genetic Roots

http://www.nature.com/ng/journal/v45...l/ng.2711.html

https://www.nimhgenetics.org/

Genetic Mental Illnesses | DNA and Mental Illness | Psychiatrist in Scottsdale

Mental Illness: The Challenge of Dual Diagnosis

First Blood Test to Diagnose Depression in Adults: Northwestern University News

Clear New Insights into the Genetics of Depression - Scientific American

Massive Study Reveals Schizophrenia's Genetic Roots - Scientific American
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
Thanks for this!
AncientMelody, angelene, ArthurDent, jelly-bean

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  #2  
Old Nov 17, 2014, 05:09 PM
jelly-bean's Avatar
jelly-bean jelly-bean is offline
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Member Since: Aug 2012
Location: Arizona
Posts: 2,564
Thanks for the list zinco. I am going to make time to read some of these things so lI have copied and pasted it so I don't lose it.
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