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Old Jan 23, 2010, 11:11 PM
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Yoda Yoda is offline
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Member Since: Oct 2006
Location: Appalachia
Posts: 9,968
I have been taking clozapine since summer 2007 for bipolar. A few times I have not refilled the Rx promptly and got manic as a result (you may have seen some of my manic posting in the past week).

When restarting the drug it seems to have a stronger sedative effect on me than when I am consistently using it. This week off the med I was sleeping about three hours/night. After restarting I slept ~ ten hours/night and have had increased fatigue during waking hours.

Has anybody else experienced anything similar with this medication?
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The purpose of life is not to be happy. It is to be useful, to be honorable, to be compassionate, to have it make some difference that you have lived and lived well. anonymous

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