[Serenity]

when you have time....Ive been reading alot lately on PSP(Progressive Supranuclear Palsy) and Im still a little at a loss...know anythign about it?I know the basics...but I more want to know the progression of it...how to guess how quickly it may set in fully...or the symptoms progress.
Second...another depression med Im not familiar with..citalopram HCL? It was given in place of zoloft which had bad side effects....would be interested in your insight and information/knowledge about it.

[CamW]

Serenity - Sorry, I'm a drug guy; I haven't even heard of PSP. As for antidepressants; those I know some things about.

Both Celexa™ (citalopram) and Zoloft™ (sertraline) are in a family of drugs called SSRIs (serotonin selective reuptake inhibitors) which help to relieve depression by boosting the brain's concentration of serotonin (a neurotransmitter that helps carry electrical signals from one nerve cell to another).

All medications have side effects. Side effects are just effects of the drug that we don't need to treat a certain condition. Sometimes side effects are advantageous; as when another SSRI, Paxil™ (paroxetine) blocks muscarinic receptors, which can lessen anxiety and help the drug treat panic disorders.

Citalopram is called the "cleanest" of the SSRIs in that it binds to and blocks the serotonin reuptake mechanism on the pre-synaptic surface in the synaptic gap, but has little affinity for other receptors. In other words, citalopram does what other SSRIs do, but not much else. Therefore, citalopram will have fewer side effects than other SSRIs, including Zoloft.

Here is a fairly comprehensive monograph of <A target="_blank" HREF=http://www.mentalhealth.com/drug/p30-c04.html>citalopram</A>

If you have anymore questions, please ask. - Cam

[Serenity]

good to be clean lol.....thanks very much for your reply and input...I will also follow up on th elink
Knowledge is power
Much appreciated