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Old Aug 17, 2011, 12:42 PM
txsnowdogsx1 txsnowdogsx1 is offline
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Location: Texas
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Has anyone with depression/general anxiety disorder ever experience sleep problems?

I normally take 100mg of Pristiq, but the nurse practitioner changed the dosage without me knowing (note to self to always double check mg dosage when getting my script!) down to 50mg. I take Xanax as needed for anxiety attacks (1mg). She also prescribed ambien because I was taking 2 otc Unisom to go to sleep at night. Within a week I noticed I could sleep, but my depression and anxiety were getting worse. Thinking it was the change in Pristiq dosage change I called them they said go back to taking 100mg (I could take 2 of the 50's). Usually within a week I am back to normal when taking Pristiq. But I noticed it has been over a week and depression does not seem to be back to normal yet. Then it clicked that Ambien had been added to the mix. I did some reading on Ambien and it said it can cause new or worsening depression - Has anyone had this effect from Ambien.

I tried a test last night only taking half a dose and there was a noticable change in my depression this morning. Is this irony? or am I onto something?

Any input is greatly appreciated.

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  #2  
Old Aug 17, 2011, 03:59 PM
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Gently1 Gently1 is offline
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Location: Canada
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Sounds like a N Practitioner question to me.

Sleeping meds did nothing for me, so seroquel 75 mg was added as an addition for mood stablizion effect and sleep. Sleep is great but exhusting dreams, especially when Therapy is intense.

Now sleeping 11 hours at night with naps during the day. Such a balancing act, for these chemicals and lifes events interaction. Makes it hard to tell what is causing what.
G
  #3  
Old Aug 17, 2011, 07:21 PM
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Jerrypharmstudent Jerrypharmstudent is offline
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Member Since: May 2006
Location: Illinois, USA
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Quote:
Originally Posted by txsnowdogsx1 View Post
Has anyone with depression/general anxiety disorder ever experience sleep problems?

I normally take 100mg of Pristiq, but the nurse practitioner changed the dosage without me knowing (note to self to always double check mg dosage when getting my script!) down to 50mg. I take Xanax as needed for anxiety attacks (1mg). She also prescribed ambien because I was taking 2 otc Unisom to go to sleep at night. Within a week I noticed I could sleep, but my depression and anxiety were getting worse. Thinking it was the change in Pristiq dosage change I called them they said go back to taking 100mg (I could take 2 of the 50's). Usually within a week I am back to normal when taking Pristiq. But I noticed it has been over a week and depression does not seem to be back to normal yet. Then it clicked that Ambien had been added to the mix. I did some reading on Ambien and it said it can cause new or worsening depression - Has anyone had this effect from Ambien.

I tried a test last night only taking half a dose and there was a noticable change in my depression this morning. Is this irony? or am I onto something?

Any input is greatly appreciated.
It really depends on the person to be honest. Ambien for many people has somewhat of a euphoric effect as it is a distant cousin to the anti-anxiety benzos. However it is possible that it could be causing increased depression, but not by the amount you are describing. Sounds to me more like the lowered Pristiq caused it and now that you've returned to the 100mg you're having to re-build up a therapeutic blood level.

However, if you continue taking Ambien and notice your depression getting worse - talk to your doctor right away.

Jerry
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Ambien - causing new or worsening depression?
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