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Default Jan 19, 2013 at 06:17 PM
  #21
Also depression is really bad for cognitive functioning.
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Default Jan 20, 2013 at 06:36 AM
  #22
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Originally Posted by hamster-bamster View Post
I do not get your logic. I was comparing AD's in hard cases to insulin for insulin-dependent diabetics.

Herbs or supplements are just substances that you ingest; there is not much of a distinction in principle between herbs and medications - you ingest something that you hope would make you feel better. Herbs grow and medications are produced, so there is that little distinction but it is not that big. If you really want to be substance-free, you would want to look at things such as therapy, exercise, improving social functioning, yoga, or whatever of that sort - those things do not involve ingesting substances.

If you want herbs, there is evidence that St John's Wort is more effective than placebo for mild to moderate depression: http://www.ncbi.nlm.nih.gov/pmc/arti...00553-0017.pdf

But it is just like with medications: you have to try it and see if it works for YOU. Clinical trials just show a tendency of the herb to outperform placebo in a group of people but not in every individual case. It gives some hope without a guarantee that it would work for YOU.
i MEANT do certain herbs/supplements work as well as meds? Thats all....
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Default Jan 20, 2013 at 02:38 PM
  #23
They are less researched but there is evidence in support of SJW that I posted. SJW needs to be discussed with the pdoc, I believe, because it has known drug interactions. But yourquestion vannot be answered in full due to fewer studies of herbs and supplements. There is good though not thoroghly conclusive evidence in support of fish oil for moods on general, and since fish oil is cheap and helps other organs of the body, why not take it? If depression is associated with and sometimes even caused by anemia, iron supplementation is recommended. Vit D helps some people. Vit D is helpful in general, for general health and disease prevention, so sure why not. And some people take more complex supplements.
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Default Jan 22, 2013 at 11:12 AM
  #24
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Originally Posted by Odee View Post
Long term use of SSRIs has simply not been researched. There's no definitely answer for how long you should be on them.

I was once described the guidelines for length of AD therapy as such: Around seven months for a first-time depressive episode after full remission of symptoms, two years for a second, indefinite after the third.

I do believe that untreated mental illness is far more deleterious to your brain than an AD. Research the facts: Depression and mental disorders damage certain parts of the brain and can cause a positive feed back cycle increasing the severity of the illness. Longer treatment on ADs before discontinuing them prevent relapse and thus prevent the destruction of mental illness on the brain.

However, if you don't feel completely better on an AD you may not be getting the protection against the effects of a prolonged illness.

what you write here has not been proven... it's a theory. Or pharma-backed propaganda. And life on untested drugs after mere three episodes?

IN fact another theory says ADs whack (not protect) your brain. They prevent your brains from producing some chemicals and whatnot naturally, create dependency. Hence why it's hard to get off. Not because of your "illness" (of which there is no proof anyways), but because your brain has been altered by those drugs.
(in addition many people's "illness" is cause by trauma, sucky relationships and sucky jobs and bad place in life. I have yet to be somebody with completely organic depression).

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Last edited by venusss; Jan 22, 2013 at 11:40 AM..
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Default Jan 22, 2013 at 12:29 PM
  #25
tnlibrarian right here on this board recently: great husband, great kids, great job, originally, and suicidality extraordinaire. It just happens more rarely but sure there is endogenous illness not exacerbated by circumstances. And she recognized herself that anyone else in her situation would have been happy... but she was suicidal. No childhood trauma, either. No exogenous explanation.

Or my friend here: three great daughters, academic husband who does not mind whatever my friend is doing, be it camping with her friends, going to the Stone Age seminars with the children, blogging, defending the rights of tortured prisoners, whatever she wants to do. Enough money from his income. Everything great. Remarkably good diet, remarkably. She exercises and is thin and petite at 50+. She published a good progressive book about fifteen years ago. Basically, an enviable life situation. Still, the usual: anxiety and depression.
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Default Jan 22, 2013 at 12:53 PM
  #26
Or this guy, Randy, whom I will be dating, I think (a very nice guy, clearly). The job is a little boring at times but, he says, the job security is such that he has to commit a criminal act to be fired by the company. A very secure company, not a start-up. Published a good technical book 10 years ago that still sells. Polyamorous by conviction and has great friendship relationships with all ex romantic partners, so no drama or crisis that most other people experience on a daily basis. Has a hobby and regularly invites members of his hobby club to his apartment for meetings, so, socialization. Goes out, so, more socialization. Does not happen to have a lot of sex life right now, but at least something and on a regular basis, so, check mark. Good income, another check mark. Loves what he is doing with computers. Watches a lot of movies, so, has some interests outside work and hobbies. So what is the problem? Nothing situational. But, reports depression for which he has finally found an effective medication after trying several bad ones. He does not have exogenous problems - it is just an endogenous illness.
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Default Jan 22, 2013 at 02:28 PM
  #27
Quote:
tnlibrarian right here on this board recently: great husband, great kids, great job, originally, and suicidality extraordinaire. It just happens more rarely but sure there is endogenous illness not exacerbated by circumstances. And she recognized herself that anyone else in her situation would have been happy... but she was suicidal. No childhood trauma, either. No exogenous explanation.
from the posts... the husband didn't seem all that great. DIdn't she complain about him quite a few times?

I have to trust you on the other two.

actually....
Quote:
defending the rights of tortured prisoners,
that sure would effect person's psyche, especially when she interacts with them, is really into it. There is something like secondary trauma.
(of course solution is NOT to drop what the person is doing... but rather be aware and learn to protect themselves...
i speak from experience, spending days reading on real life bad stuff can mess up person's mind... that's why so few actually get involved).

and as for randy... how long did you know him? Maybe **** will come up. I know with most people who defended "broken brain, chemical imbalance" often do indeed have traumas little or big ones in their life.

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Default Jan 22, 2013 at 05:03 PM
  #28
tnlibrarian complained that H was saying that if she does not harass and abuse him and have rages against him, then she is not bp and needs to suck it up. That does not portray him as a bad person but rather a very uninformed one - he must have read, very briefly, a little blurb about the disease, the rages and mistreatment of spouses caught his eye, he disregarded the other 99%, and reacted to what he thought was relevant. In turn, she did not like that. But it was not his abusing her or mistreating her or anything like that. Just, suboptimal response to the illness in the spouse.

Randy - yes, we will see. But then everyone can be said to have issues...

The was a thread on relationships and communications here. A guy is married and the wife had what is called "an emotional affair" and ended it. I do not know what an emotional affair is, but whatever, she ended it. She is the guy's best friend. She talks to him about their vacation together. She does not turn his children against him. She does not abuse him or anything. She does not gamble his money. She just is unsure that she is actively in love with him and when she is sick and he gives her crackers and ginger ale, she does not show visible, positive signs of appreciation. And that is the extent of it. And she goes into therapy with him, and does not raise the issue of divorce at all. Just an emotional affair in the past and lack of visible appreciation of his efforts in the present. No other bad deeds on her part. He is seriously sad. Well, in that case, his underlying biological depression, which preceded the emotional affair, in other words, which started under the circumstances that were EVEN BETTER than the current circumstances, affects how he reacts to the stressors which I would call minor. And when it is being pointed out to him - look, in the best case scenario, the marriage survives, in the worst case scenario, it does not, but you would split up amicably without animosity as civilized people and co-parent happily for the rest of your lives, what is so bad about it?? - he agrees, that yes, his situation is not so bad compared to what it could have been. But he has something underlying or else he would have been more upbeat. He needs something, I am not sure what, or a combination of things, may be CBT to reframe catastrophic thinking and mindfulness to learn to appreciate the moment at least a bit. A lot of guys would be ecstatic to have a wife who plans vacations together with them.
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Default Jan 22, 2013 at 05:30 PM
  #29
The friend who participates in the defense of tortured people - my point was that she has a very tolerant husband. She, at one point, caught a rat. By accident. What did she do with the rat? She cooked it... and ate it. She used the skills she learned in her Stone Age workshops. And the husband, who is the exact opposite and never camps and enjoys the vacations with all the luxuries the modern world has to offer, was not disgusted. He did not eat the rat, but he was, like, whatever. She wants to do social causes such as with tortured people - fine. She has not done anything for money for years and years, despite being a Harvard Law School graduate. She did want the stress and hours connected with the legal career. He has always been fine with everything.

So if you imagine the spectrum of husbands from the most abusive on the left to the most tolerant on the right, her husband would be on the very, very far right - off the spectrum, in fact. Some of the common friends wonder how he is SO tolerant. Because, you know, the incident with the rat is unusual, to say the least.

So her situation is enviable. A lot of people would give a lot to be in her shoes.

But she has depression and her mother is schizophrenic. No abuse in her family of origin either, her father is very sweet and caring and took early retirement to care for his wife, so peace and quiet. But - mental illness.
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Default Jan 22, 2013 at 05:36 PM
  #30
I am not saying relationships are the ONLY factor. Your friend seems one of the intelligent people who kinda drive themselves crazy. Maybe depression comes with high IQ. I have not met person with high iQ without issues.

But was just opposing the whole "depression destroys your brain and ADs protect it" claim. Especially since this "illness" is very hard to define.

I could come up with claims of past life, hypersensitivity, psychiness... but that's kinda far off in drug forum, heh.

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Default Jan 22, 2013 at 05:37 PM
  #31
Yeah, past life would be far off.

Well you cannot graduate from Harvard Law School without a high IQ - the test used to get into law schools correlates with IQ, so no way out of it.
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Default Jan 22, 2013 at 05:42 PM
  #32
I think more people believe in past lives though than in "chemical imbalances". I do have my own sets of how past existences influence us. and many found exploration in that domain helpful.



let's not OT this though.

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Default Jan 22, 2013 at 08:13 PM
  #33
yes, that would be very tangential.
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Default Jan 22, 2013 at 11:52 PM
  #34
I guess that I should have placed a much heavier disclaimer on my post aside from "I believe..."

Now I believe that it is very factual that mental illness has deleterious effects on the brain. This is what I meant by 'researching the facts.'

The question of whether ADs are good, bad, better, or worse in this situation is no where near a solid answer or even a tenuous one.

My last comment about the AD not working was kind of a shrug: If OP's med is not working for mood than there's not much reason to think it could be working for a hypothesized 'neuro-protecting' factor. So even if there's a potential long term benefit, I don't see how OP can experience possible benefit if the med isn't keeping the illness at bay in the first place.

But otherwise, long term AD use to prevent relapse seems is how Psychiatrists prescribe them.

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Default Mar 13, 2013 at 04:51 PM
  #35
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No, they don't "stop working".
The human body/brain does not build up a tolerance to SSRI's like most other drugs.
You are misinformed. They can and do "poop out."

Google it.
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Default Mar 14, 2013 at 02:40 AM
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Re: meds "pooping out". Not all depression is due to low serotonin. If you're taking an SSRI and it works for a while, then "poops out", it's likely that you are having depressive symptoms due to a different chemical issue than serotonin. For example, low norepinephrine or low dopamine. It's not so much that the med poops out, but rather that it no longer is the appropriate one to use.
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Default Mar 14, 2013 at 10:52 AM
  #37
If your AD quits working it is time to get force ful with doc about an other AD, as they do quit working. Four years and my zoloft just quit 3 months ago and I end up back in the hospital. Finally got forceful as they just wanted to up the zoloft, I was already taking 200mg and add Welburin 150 xl That made me go pcyhco. I am now on prestiq (it is liver frendly) and I am back to my fat happy self, praise the Lord. I have also started losing weight since going on Prestiq and I am even getting some sex drive again. Not bad for being almost 60, the Zoloft had pretty much wipe it out. Be Kind To Yourself and God Bless. Garry J
I think treating mental illness is a crap shoot and some times takes awhile to win.
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Default Mar 15, 2013 at 06:53 AM
  #38
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Re: meds "pooping out". Not all depression is due to low serotonin. If you're taking an SSRI and it works for a while, then "poops out", it's likely that you are having depressive symptoms due to a different chemical issue than serotonin. For example, low norepinephrine or low dopamine. It's not so much that the med poops out, but rather that it no longer is the appropriate one to use.
yeah, but what do u take if you have low dopamine
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Default Jun 25, 2013 at 01:18 AM
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Re: meds "pooping out". Not all depression is due to low serotonin. If you're taking an SSRI and it works for a while, then "poops out", it's likely that you are having depressive symptoms due to a different chemical issue than serotonin. For example, low norepinephrine or low dopamine. It's not so much that the med poops out, but rather that it no longer is the appropriate one to use.
?? Sounds complicated...
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Default Jun 25, 2013 at 07:09 AM
  #40
Back to the original question................. How long should you take an SSRI? You take it for as long as you need to. Maybe months, maybe years. Does a diabetic stop taking insulin? No because they need it. Same to for depression. You go by what your body is telling you. No two people are the same. That's why there are so may meds around and some many dosages.

When and if thing change you deal with it at that point. Always something new on the market. SNRI's are also an option. Ask the person who is prescribing things for you and dont stay on a medication if it makes you feel unwell.

I have been on some kind of mental illness meds for 28 years. I stopped for two years and crashed and burned. The side affects they talk about are after taking them long term. Dry mouth may affect affect your teeth and eyes. So always keep your water up and have chewing gum to stimulate your saliva glands.
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