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  #1  
Old Nov 07, 2017, 03:19 PM
Americano Americano is offline
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I’m on two ssris and lamictal. I’ve considered going from the two to just cymbalta because it’s the only other one easy to tolerate but I hear it’s hard on the liver. Also considering taking ssri and tca. Just trying to put the least toxins in my body as I have to.

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  #2  
Old Nov 08, 2017, 08:30 AM
still_crazy still_crazy is offline
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hi. id avoid tca drugs, if you can. especially w/ other drugs in the mix, you could expose yourself to some serious long term risks.

cymbalta can go up to 120 (off label, but safe). if you continue having problems, some doctors have added remeron to ongoing cymbalta treatment w/ good results (although there's a higher risk of agitation, hypomania, etc.).

id personally avoid taking two ssri drugs, at the same time. that's just me, though. serotonin syndrome scares me. if it helps w/ obsessive thoughts and such, then maybe you'd be better off getting the doctor to max out 1 ssri and add something, like a low dose newer tranquilizer, buspar, etc.

cymbalta -can- cause elevated liver enzymes and i think there have been some cases of serious problems, but i dont think its common. effexor works somewhat differently, but effexor doses can range from 75mgs all the way up to 450+, so maybe effexor would be a good option for you?

hope this helps.
  #3  
Old Nov 08, 2017, 01:40 PM
Wonderfalls Wonderfalls is offline
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I take two drugs for depression, Wellbutrin and Lamictal, but no SSRI's. If one is not doing the job then I would ask for an extra med from another category, or you could add something like Abilify medically approved to work with your SSRI's.
  #4  
Old Nov 08, 2017, 01:50 PM
Americano Americano is offline
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Quote:
Originally Posted by still_crazy View Post
hi. id avoid tca drugs, if you can. especially w/ other drugs in the mix, you could expose yourself to some serious long term risks.

cymbalta can go up to 120 (off label, but safe). if you continue having problems, some doctors have added remeron to ongoing cymbalta treatment w/ good results (although there's a higher risk of agitation, hypomania, etc.).

id personally avoid taking two ssri drugs, at the same time. that's just me, though. serotonin syndrome scares me. if it helps w/ obsessive thoughts and such, then maybe you'd be better off getting the doctor to max out 1 ssri and add something, like a low dose newer tranquilizer, buspar, etc.

cymbalta -can- cause elevated liver enzymes and i think there have been some cases of serious problems, but i dont think its common. effexor works somewhat differently, but effexor doses can range from 75mgs all the way up to 450+, so maybe effexor would be a good option for you?

hope this helps.
Why avoid tcas? Is it the dementia risk your referring to?
  #5  
Old Nov 08, 2017, 09:49 PM
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~Christina ~Christina is offline
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I have dumped many meds due to the effect on my liver of kidneys . Id like to keep both in good working order .

I suggest you talk to your Pharmacist they really know the ends and out of meds and how they can effect your body
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  #6  
Old Nov 09, 2017, 12:20 PM
Americano Americano is offline
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Quote:
Originally Posted by ~Christina View Post
I have dumped many meds due to the effect on my liver of kidneys . Id like to keep both in good working order .

I suggest you talk to your Pharmacist they really know the ends and out of meds and how they can effect your body
Good idea! What were some that where too toxic for you?
  #7  
Old Nov 10, 2017, 06:52 PM
Seqoya Seqoya is offline
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Quote:
Originally Posted by Americano View Post
I’m on two ssris and lamictal. I’ve considered going from the two to just cymbalta because it’s the only other one easy to tolerate but I hear it’s hard on the liver. Also considering taking ssri and tca. Just trying to put the least toxins in my body as I have to.
Just to let you know. Medical Professionals can check your liver function periodically to make sure it's doing well. If it's not even just a little and you're taking a medication that could be contributing to that. They say they will catch it very early.

That's what I have been told by doctors. I am not a medical professional that is qualified to give medical advice. So you might want to speak to a qualified family physician and a psychiatrist about this issue if you so choose.
  #8  
Old Nov 10, 2017, 11:16 PM
Americano Americano is offline
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Originally Posted by Seqoya View Post
Just to let you know. Medical Professionals can check your liver function periodically to make sure it's doing well. If it's not even just a little and you're taking a medication that could be contributing to that. They say they will catch it very early.

That's what I have been told by doctors. I am not a medical professional that is qualified to give medical advice. So you might want to speak to a qualified family physician and a psychiatrist about this issue if you so choose.

I am aware of this, I’d rather go ahead and start on something with the best safety profile to start with.
  #9  
Old Nov 11, 2017, 12:43 AM
Seqoya Seqoya is offline
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I see. It's up to you of course, Americano.
  #10  
Old Nov 11, 2017, 10:49 AM
Americano Americano is offline
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I just can’t seem to find out which ones are the least toxic, seems like this would be important haha. Maybe I’ll just try to move over to 5htp and SJW however I’m still not even sure that they are safer even though natural
  #11  
Old Nov 12, 2017, 04:22 PM
Wonderfalls Wonderfalls is offline
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There are all kinds of poisons that are "natural" like arsenic and snake venom; doesn't mean "natural" is safer. Also all drugs have the potential to harm you, counting everyday drugs that people buy over the counter. I don't think anyone has researched "least toxic" on the drugs you're talking about. The trick is to take what you need to make your life at least bearable,or hopefully better than that, and not to take any more than you need.
  #12  
Old Nov 12, 2017, 06:37 PM
Americano Americano is offline
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Originally Posted by Wonderfalls View Post
There are all kinds of poisons that are "natural" like arsenic and snake venom; doesn't mean "natural" is safer. Also all drugs have the potential to harm you, counting everyday drugs that people buy over the counter. I don't think anyone has researched "least toxic" on the drugs you're talking about. The trick is to take what you need to make your life at least bearable,or hopefully better than that, and not to take any more than you need.
Note: This is going to come across like a jerk. I realize I should have just ignored it, as I wasted my time to pick apart your post. I hope you can take it lightly. And I do apreciate you posting, please feel to do so again.

Nothing about this post makes sense.
1) I didn't mention natural products being safer, I stated I was unaware of the safety.
2) Sentence #2.. this is the reason I made this post to find comparative toxic levels easily.
3) sentence #3... of course they have use google, I'm just looking for a user friendly source of information.
4) sentence #4... yes obviously that is the point. I'm trying to get there and survive for a while!
  #13  
Old Nov 13, 2017, 12:58 AM
Americano Americano is offline
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I was going to erase that post but it looks like it won’t let me...enjoy lol
  #14  
Old Nov 13, 2017, 03:29 PM
Wonderfalls Wonderfalls is offline
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Quote:
Originally Posted by Americano View Post
I was going to erase that post but it looks like it won’t let me...enjoy lol
Don't worry; it's perfectly fine with me. Sorry you haven't gotten what you want.
  #15  
Old Nov 13, 2017, 11:24 PM
Americano Americano is offline
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Thanks for understanding I felt guilty ha
  #16  
Old Nov 16, 2017, 01:34 PM
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WildcatVet WildcatVet is offline
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Go to Drugs.com and you can research each individual medication.
Drugs.com
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Bipolar l/Rapid/Mixed/Depression/Anxiety Disorders

lamotrigine 100mg 2x/day
Vraylar 6mg 1x/day
methylphenidate 10mg 3x/day
bupropion XL 200mg 2x/day
bupropion IR 174mg 1x/day
buspirone 30mg 2x/day
quetiapine 50mg 1x/day



I'm 50 Shades of Bipolar and I have no safe word...
Thanks for this!
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  #17  
Old Nov 16, 2017, 09:53 PM
mugwort2 mugwort2 is offline
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Its a damn shame many if not most of these psych drugs are so toxic. Many causing heart problems, diabetes and other major serious health problems. Studies show that consumers on average live at least ten years less than people not on them.
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