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#1
Jul 04, 2019, 09:42 PM
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I'm on 150mg Invega Sustenna every 3 weeks.
150mg divided by 21 days = 7.1mg of paliperidone palmitate every day. 12mg Invega XR in pill form or 15mg is the max dose. That's like double the amount that is in the injection and most people take Invega Sustenna injection every 4 weeks so 150mg divided by 28 days = 5.4mg a day. Is paliperidone palmitate stronger than just paliperidone or something? What sorcery is this??? |
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#2
Jul 04, 2019, 10:35 PM
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Usually the mg dosage for an XR version of a drug is the amount in the whole pill across time, not the amount that becomes bioavailable (able to be used by your body/in your bloodstream) at a single moment in time. It sounds like the XR version of your drug probably comes in two waves. This means you swallow the pill, something dissolves quickly in your GI tract, and the first 7.5 mg are available. By the time its effects wear off, the slower dissolving other half (the other 7.5 mg) are starting to become bioavailable. Both halves together make the total 15 mg. Also, drugs rarely have a linear/constant rate of onset and tapering off. Scientists who create XR drugs keep this in mind so the two halves of the XR pill work more smoothly together (i.e. the slow wearing off of the first half might overlap with the slow coming on of the second half to create a a more optimal blood level of the drug at that given time). For a theoretical example, taking two instant release pills of 10 mg every 4 hours is like taking one extended release version of 20 mg that lasts 8 hours.
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"I think I'm a hypochondriac. I sure hope so, otherwise I'm just about to die." PTSD OCD Anxiety Major Depressive Disorder (Severe & Recurrent) |
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#3
Jul 05, 2019, 08:19 AM
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Idk but I was on 234mg invega sustenna injections and they said it was the max dosage... now I take 12mg per day which they say is the max for daily tablets
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#4
Jul 05, 2019, 08:50 AM
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Quote:
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“All the darkness in the world cannot extinguish the light of a single candle.” -St. Francis of Assisi Diagnosis: Schizoaffective disorder Bipolar type PTSD Social Anxiety Disorder Anorexia Binge/Purge type |
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