advertisement
Reply
Thread Tools Display Modes
brainfog
Member
brainfog has no updates.
 
Member Since: Apr 2014
Location: United States
Posts: 28
8 yr Member
1 hugs
given
Default Aug 25, 2021 at 12:27 PM
  #1
Hi there,
My pdoc raised my dose of Prozac to 40mg and I had a great response. Now I'm getting the same yucky feeling which leads me to believe I need more. What in your experience is the next dosing jump, 50 or 60, and how long do I have to be on 40 before raising?
Many thanks!
brainfog is offline   Reply With QuoteReply With Quote

advertisement
Cassoway
Junior Member
Cassoway has no updates.
 
Member Since: Aug 2021
Location: Liverpool
Posts: 16
2 yr Member
21 hugs
given
Default Aug 25, 2021 at 12:32 PM
  #2
I am on 60 which I have been told is the max possible which was a lift from 40mg after a years. Not sure how much impact the extra 20mg had to be honest.

__________________
We rise by lifting others
Cassoway is offline   Reply With QuoteReply With Quote
mikrw33
Member
 
mikrw33's Avatar
mikrw33 has no updates.
 
Member Since: Jan 2013
Location: Madison, Alabama, USA
Posts: 40
10 yr Member
3 hugs
given
Default Sep 15, 2021 at 02:44 PM
  #3
What do you mean by the yucky feeling you mention?

Typically from 40 mg, the next step would be 60 mg, and then 80 mg if you needed it. 80 mg is usually the very highest dose, but in very rare cases, the dose can be increased to as much as 120 mg (usually reserved for extremely treatment-resistant OCD).

For Prozac, dose increases tend to take a little longer to assess whether they're going to work or not. I would say probably 3-4 weeks minimum based on its very long half-life. (The longer the half-life, the longer a medicine takes to reach steady-state blood levels.)

There are some studies that actually suggests that lower doses of Prozac (i.e. 20 mg) are actually better for depression than higher doses. Higher doses tend to be better for anxiety (and depression with anxiety).
Dose-response relationship of recent antidepressants in the short-term treatment of depression

Quote:
The studies with fluoxetine did not show significant differences in terms of clinical efficacy across a dose range of 20 to 60 mg/day Even a dose of 5 mg/day was effective compared with placebo (Table I) 1 Therefore, for the majority of patients, there is no advantage of increasing the dose of fluoxetine above 20 mg/day. It might even be the case that the higher dose of 60 mg/day is less effective in major depressive disorder.

__________________
Diagnoses: Tourette's Disorder, OCD, ADHD-PI, Bipolar I Disorder, Borderline Personality Disorder, Anxiety Disorder Unspecified

Medications:
Dyanavel XR 15 mg 30 mg/day
Lamictal 300 mg/day
Cymbalta 90 mg/day
Lunesta 3 mg/night
Dayvigo 10 mg/night
mikrw33 is offline   Reply With QuoteReply With Quote
All times are GMT -5. The time now is 08:00 PM.
Powered by vBulletin® — Copyright © 2000 - 2024, Jelsoft Enterprises Ltd.



 

My Support Forums

My Support Forums is the online community that was originally begun as the Psych Central Forums in 2001. It now runs as an independent self-help support group community for mental health, personality, and psychological issues and is overseen by a group of dedicated, caring volunteers from around the world.

 

Helplines and Lifelines

The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.

Always consult your doctor or mental health professional before trying anything you read here.