Partial response to Olanzapine

185329 · Mar 15, 2023 at 03:07 AM

I am on 30mg Olanzapine, and yet I feel like I have only partially responded. Has anyone else had this problem? If so, what did you do? Would Clozapine be a good alternate option?

SlumberKitty · Mar 15, 2023 at 10:21 AM

I am no expert. I thought 20 mg was the highest you could go on Olanzapine. Have you tried Lybalvi? It is Olanzapine and something else. It is supposed to be better metabolically. I tried to take it but it was SO sedating I couldn't handle it. So I went back on Olanzapine. I also take Latuda in conjunction with the Olanzapine because Olanzapine alone wasn't enough. Has your doctor thought of augmenting with something else? I don't know about Clozapine personally because I have never been on it. But I think it is supposed to be really good. So it might be a good option. Do you have a psychiatrist or do you get your meds through your primary care physician? I see a neuro-psychiatrist and he has been really helpful. He doesn't take insurance so he is really expensive but he has probably saved my life. Good luck to you. Let us know how it goes. Hugs if wanted, Kit

185329 · Mar 15, 2023 at 07:30 PM

Thanks, Kit. I have never tried Lybalvi. And you are right that 20mg is the maximum recommended dose for the Olanzapine. I have been on Rexulti as an adjunct to my Olanzapine in the past. And it seemed to be helping a lot. I get my meds through my psychiatrist. He is covered by insurance, but frankly, I don't think he really cares. I have been seeing him for more than a year and all he seems to care about is getting paid. The psychiatrist I was seeing before him was not covered by insurance, but I could tell that he actually cared about my well-being. He was the one that prescribed me Rexulti in addition to my Olanzapine.

My Mother thinks I am on too much medication right now, so I am not really sure if I should inquire about going back on the Rexulti to my current psychiatrist. My guess is that I should just keep my regimen the same for now. I am on Olanzapine 30mg and Escitalopram 30mg.

SlumberKitty · Mar 16, 2023 at 11:44 AM

I used to take Rexulti. It helped but it also made me gain a lot of weight. So that was annoying.

WastingAsparagus · Mar 17, 2023 at 02:56 PM

You could also inquire about aripiprazole. I am on that, and it helps my depression immensely. If that is a concern to you. I am not sure what your main concern is. You said you partially responded to the olanzapine. Does that mean you have psychotic symptoms still? Are you depressed?

185329 · Mar 17, 2023 at 10:59 PM

Quote:

Originally Posted by WastingAsparagus

You could also inquire about aripiprazole. I am on that, and it helps my depression immensely. If that is a concern to you. I am not sure what your main concern is. You said you partially responded to the olanzapine. Does that mean you have psychotic symptoms still? Are you depressed?

I cannot really tell if I am having psychotic symptoms still. I am not sure if I am depressed, either. When I was on Rexulti in addition to what I am on now, there was no question about it. I was definitely sane when I was on Rexulti as an adjunct. And I was definitely not depressed.

But the problem is that I have a lot of side-effects from what I am on right now. And I am not sure if I should add another medication. Thanks for your concern.

WastingAsparagus · Mar 18, 2023 at 02:26 PM

Quote:

Originally Posted by 185329

I cannot really tell if I am having psychotic symptoms still. I am not sure if I am depressed, either. When I was on Rexulti in addition to what I am on now, there was no question about it. I was definitely sane when I was on Rexulti as an adjunct. And I was definitely not depressed.

But the problem is that I have a lot of side-effects from what I am on right now. And I am not sure if I should add another medication. Thanks for your concern.

Ah I understand. Yes, I too was on olanzapine. Obviously I'm not telling you what to do but you could at least inquire about lowering the dose of olanzapine because you're having side effects. And then perhaps inquire about the Rexulti?

And yes, of course. I think if you expressed what you just wrote in that message to your psychiatrist in a kind way, perhaps that psychiatrist would understand.

185329 · Mar 19, 2023 at 10:59 PM

Quote:

Originally Posted by WastingAsparagus

Ah I understand. Yes, I too was on olanzapine. Obviously I'm not telling you what to do but you could at least inquire about lowering the dose of olanzapine because you're having side effects. And then perhaps inquire about the Rexulti?

And yes, of course. I think if you expressed what you just wrote in that message to your psychiatrist in a kind way, perhaps that psychiatrist would understand.

Thanks. My appointment is tomorrow. I plan on telling him that I have been sleeping way too much, and see what he says. And yes, maybe I could express my thoughts about thinking that all he cares about is getting paid; and that he does not care about my well-being.

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Partial response to Olanzapine

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185329 Member 185329 has no updates. Member Since: Jul 2021 Location: North America Posts: 152 1 hugs given	Mar 15, 2023 at 03:07 AM #1 I am on 30mg Olanzapine, and yet I feel like I have only partially responded. Has anyone else had this problem? If so, what did you do? Would Clozapine be a good alternate option?
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SlumberKitty Legendary Wise Elder SlumberKitty is staying stable. Member Since: Jul 2018 Location: CA Posts: 27,030 (SuperPoster!) 117.8k hugs given	Mar 16, 2023 at 11:44 AM #4 I used to take Rexulti. It helped but it also made me gain a lot of weight. So that was annoying. __________________ Dum Spiro Spero IC XC NIKA
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