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Mountaindewed
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Default May 27, 2024 at 10:16 AM
  #1
I had my lamictal increased from 75mg to 100mg and my Prestiq increased from 25mg to 50mg last Thursday and I'm still lying in bed and feeling worn out and not wanting to leave my house and stuff.

I'm guessing it takes more then a few days to see a difference but how long?

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Default May 27, 2024 at 01:55 PM
  #2
I know that small of a lamictal increase would probably be a very subtle improvement over a week or two, maybe getting another bit o' improvement for about a month after the increase. Lamictal did nothing for me until 200mg though.

They say therapeutic dose and generally starting dose for Prestiq is 50mg. Generally antidepressants take a couple weeks to kick in. It has a short half-life so I wouldn't think starting at 25mg would drastically shorten that despite having some in your system already.

I'd give it at least two weeks before expecting any noticeable improvement and a month maybe two before seeing if you get where you want to be with depression symptoms/mood instability/probably anxiety (not approved for that, but Effexor is and they're almost the same thing. Prestiq is I believe used off label because of this and the fact it has less side effects than Effexor).

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Default Jun 15, 2024 at 02:11 AM
  #3
I'm not sure how long mood stabilizers take to work but I took all of them and none of them worked for me. Majority of anti-depressants take 6 wks to work. I took Pristiq for 4 wks and felt horrible so I went inpatient at Johns Hopkins and they never helped me just like every other hospital. I took Lithium for 15 yrs and didn't do a thing to me.

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