[Tart Cherry Jam]

I saw my gynecologist in September and weighed the risks and benefits of starting HRT early. I was 51 then and probably perimenopausal and I say probably because I wear Mirena without periods, with just occasional very mild spotting, so I would not know if my periods became less regular, and I do not have any symptoms associated with perimenopause but age-wise one would expect me to be in perimenopause. So I took into account the pros and cons as they apply to my particular situation and thought that on balance, all things considered, I want it. And we started with the tiny lowest dose of the transdermal patch. I did not need separate progesterone because Mirena provides that already.

I then began having diarrhea and a very bad case of it. I normally have a very well functioning GI tract and it was "out of character". It is not at all a common side effect of estradiol and the gynecologist attributed it to Ozempic I am taking for weight loss and blood glucose control (it allowed me to stop being prediabetic and reverse the weight gain from Zyprexa). Indeed Ozempic comes with a whole panoply of GI side effects including diarrhea, but in my case stopping Estradiol improved the situation and since then I have had occasional diarrhea but it was not as nearly as bad. But it did happen off Estradiol so maybe the gynecologist is right and I should ascribe the side effect to Ozempic.

I am wondering if anybody has been on Estradiol patches and not on Ozempic and still has had diarrhea.

Also a thought that maybe the interaction between Estradiol and Ozempic caused it, but I used the drug interactions checker on Drugs.com and this is not listed.

[steelmagnolia65]

Originally Posted by Tart Cherry Jam

I am wondering if anybody has been on Estradiol patches and not on Ozempic and still has had diarrhea.

I have used Estradiol patches before (no Ozempic), and didn't have any diarrhea.

Maybe your gynecologist is correct?.......For what it's worth, one of my friends started Ozempic, and had such terrible diarrhea, that she had to switch to another medication.

[Tart Cherry Jam]

I will retry Vivelle-Dot and see what happens. Thank you.

[steelmagnolia65]

Originally Posted by Tart Cherry Jam

I will retry Vivelle-Dot and see what happens. Thank you.

@Tart Cherry Jam, I hope the Vivelle-Dot will work out for you......It really helped me when I used it...

[Tart Cherry Jam]

Originally Posted by steelmagnolia65

@Tart Cherry Jam, I hope the Vivelle-Dot will work out for you......It really helped me when I used it...

I am on a second day of retrying it. First day, slight diarrhea. Today, no BM. This is not different from the all-over-the-place pattern I had had on Ozempic before. So I think now that Vivelle-Dot will work out for me, that I will be able to use it. I am so happy. I wanted to use it preventatively to stay ahead of the curve. I am very glad it helped you...

[Tart Cherry Jam]

It works! the Gi trouble comes and goes, but it is caused by Ozempic, not vivelle-dot. Vivelle-dot gives me no side effects and I am very happy with it, as something I am doing prophylactically against possible menopause symptoms in the future.