If someone is bipolar the ADs can cause severe agitation which I've experienced. Celexa and others did that to me.
I also had a complete Summer of ECT which sent me to the lowest physical and mental states I've ever experienced. I could not go thru that again.
Bottom line is PDOCs don't know a great deal about mood disorders and I believe they lead their patients on. One PDOC lead me on for several yrs and took tens of thousands of $ from me for poor med mgmt and zero psychotherapy. He begged me to stay when I told him I was looking for another PDOC.
Now you are seeing tons of Lawyer commercials on TV for ADs like Paxil, Zoloft regarding birth defects that these drugs can cause.