Use it at night mostly, dabbed lightly around the eye for a fresh look in the day. I have know some of the women using it during the day in crunch and putting it on under their makeup. No matter when applied, models and flight attendants have been using this trick with prep H for some time. I am not so sure I would use more than once a day as their are no studies for this use. I have only used it in a pinch for really bad days such as the effects when have consumed too much salt accidentally or when traveling wreaks havoc on my bags, but use specifically designed eye creams normally, like the Oil of Olay product you are using currently. I have not tried that one though, and would love to know what you think of it; please let us know if you have a chance.