To answer the question in you title it is yes. If you can manage to come out of a depression by whatever means then yes I have found all the normal interests and motivations come back. I won't say happy joyous and free because I rarely get that. My normal state is moderate to mild. I have probably said "I don't care" more than any other saying in my whole life. But when I am not in a total depression things are much much better and I do actually care about a lot of things.