Yes yes yes yes!!! I was constantly fatigued. Always complaining to the doctor. Existing off of energy drinks and soda. I was prescribed Wellbutrin and I dropped five pounds shortly after because I stopped drinking sodas everyday. I think it works perfectly. But I think it also can depend on your dosage and which formulation. XL kept up at night, but switching to SR helped with that. I've heard on here that it makes some people manic, but I haven't had that problem. Perfect compliment to my Trileptal in my opinion.