For me it's cyclical. I generally have accepted it and what the effects on my life have been. Then I go through a spell like I have been doing recently where I am just so frustrated by the things I wish were in my life that aren't because of bipolar. I've been talking about this a lot in therapy recently and my therapist has been reminding me that I am sad over real losses, not just feeling sorry for myself (my default thought). We'll talk about it for a while longer then I'll be done again for a while but sometime it will come back. And then it will go away again.