If it's my stuff, I acknowledge it but then let it go and behave to the other person as if there is no problem/normally or acknowledge their comment (if it's about me at all) and move on with the relationship.

If someone is giving me information about myself ("sometimes you are hard to be around") then I just do an "I know" response and try to cool those sorts of things that are difficult for the other person :-) or, if I'm in an okay place I ask for specifics so I can work on them. If it is just that the other person is doing something else and doesn't have time for me or something like that, I acknowledge my sadness that I wish they were available to myself and then find something else or to do/occupy myself with or someone else to play with :-)

But like pachyderm says, I analyze the situation and see what's going on with me, whether it is in fact my stuff or not and then figure out what to do from there. I think posting here at PC is a good thing to do in that situation.