[sunnydisposition]

Hello everyone, i was wondering if i could pick your brain on this matter. Any suggestions would be greatly appreciated.

How often should one get tested for serum Cholesterol, Triglycrides, Thyroid function, Blood sugar while taking AAP's for long term?

Are all these adverse effects possibly dose dependant? Would staying at lowest possible dosage give me better odds of not experiencing these side effects?

Is it possible that i may not experience any of these side effects at all?

Out of all AAP's which one (in general) is less likely to cause these adverse effects?

[ThunderGoddess]

I am on seroquel which is why I opened this thread but I highly suggest these questions be answered by a doctor.

Originally Posted by Ravdeep Singh

How often should one get tested for serum Cholesterol, Triglycrides, Thyroid function, Blood sugar while taking AAP's for long term?

I had my blood tested:
(1) Before I took my AAP (to get a baseline)
(2) Two weeks after I took my AAP
(3) One month after I took my AAP

and now I get it tested once a year.

I'm not sure if that's how often you should get it done, but that's what happened when I tried Latuda. Then the same thing happened when I tried Abilify.

Originally Posted by Ravdeep Singh

Are all these adverse effects possibly dose dependant? Would staying at lowest possible dosage give me better odds of not experiencing these side effects?

Yes, they can be dose dependent: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203261/

"Metabolic changes, as seen by dose-dependent elevations of cholesterol, triglyceride, LDL and VLDL concentrations within 6 weeks of risperidone therapy, are other atypical features seen in our patient."

Originally Posted by Ravdeep Singh

Is it possible that i may not experience any of these side effects at all?

Possible. It depends on your body chemistry. For example, I'm 25, on the very thin side, I exercise a lot, and yet I have high cholesterol. It has nothing to do with weight, height, age, etc.. So it's really a luck of the draw, hate to say it.

And the funny thing is, my triglycerides are actually really low -- 48. I think it's because I exercise a lot and am not overweight. Yet, my HDL is really high, and it kept increasing with Latuda.

Originally Posted by Ravdeep Singh

Out of all AAP's which one (in general) is less likely to cause these adverse effects?

That's a tricky question.

I think (note: *I think*) that all AAPs carry the same risks of affecting your blood (high cholesterol, high blood glucose, etc.). At least, I haven't seen an AAP that *doesn't* carry that risk. (See: Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro)

I believe there are some APs that don't carry this risk, but not AAPs. You'll have to double check with your doctor on that though... because I'm not 100% sure.

[sunnydisposition]

Originally Posted by bluebicycle

I had my blood tested:
(1) Before I took my AAP (to get a baseline)
(2) Two weeks after I took my AAP
(3) One month after I took my AAP

and now I get it tested once a year.

I'm not sure if that's how often you should get it done, but that's what happened when I tried Latuda. Then the same thing happened when I tried Abilify.


Yes, they can be dose dependent: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203261/

"Metabolic changes, as seen by dose-dependent elevations of cholesterol, triglyceride, LDL and VLDL concentrations within 6 weeks of risperidone therapy, are other atypical features seen in our patient."


Possible. It depends on your body chemistry. For example, I'm 25, on the very thin side, I exercise a lot, and yet I have high cholesterol. It has nothing to do with weight, height, age, etc.. So it's really a luck of the draw, hate to say it.

And the funny thing is, my triglycerides are actually really low -- 48. I think it's because I exercise a lot and am not overweight. Yet, my HDL is really high, and it kept increasing with Latuda.


That's a tricky question.

I think (note: *I think*) that all AAPs carry the same risks of affecting your blood (high cholesterol, high blood glucose, etc.). At least, I haven't seen an AAP that *doesn't* carry that risk. (See: Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro)

I believe there are some APs that don't carry this risk, but not AAPs. You'll have to double check with your doctor on that though... because I'm not 100% sure.

Thanks so much for such aptly put reply Blue bicycle. You've put my mind at ease. I can now better plan for my health care.

[CobolCapsule]

Get blood work once a year, and most of the side effects from AP's are rare and some are dose dependent.

[Rjaye]

Talk with your doctor about a blood work schedule. My doctor and I have worked out a schedule for blood work, and she has standing orders so I can go in on the dates decided to have my blood drawn, and I don't have to go visit my doc each time to get an order for blood work. Then if anything of concern shows up, they call me with advice or to schedule a follow up appointment. It's been really handy.