[metamorphosis12]

Inflammation in the body is one of the leading causes of disease, including mental disorders. Here are some recent articles and studies on the topic of mental illness, anxiety, stress, sleep quality and physical and emotional degradation.

Original article, I read was the starting point-
http://psychnews.psychiatryonline.or...11%2F09%2F2012

My main body of text and research-
Cox-2 (cyclooxygenase-2): an enzyme that makes prostaglandins that cause inflammation and pain and fever
Cox-2 inhibitor: an anti-inflammatory drug or natural compound that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1

A Beginning Abstract:
http://www.ncbi.nlm.nih.gov/pmc/arti...eport=abstract

Full Text:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391987/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421432/

The Basics- "exercise and select diets exert their effects by affecting molecular events related to the management of energy metabolism and synaptic plasticity"-
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258093/

Natures potent arsenal of ant-inflammatory and neuroprotective agents~
"Curcumin, quercetin, green tea catechins, balcalein, and luteolin have been extensively studied, and they demonstrate important effects on cell signaling that go far beyond their antioxidant effects. Of particular interest is the effect of these compounds on immunoexcitotoxicity, which, the authors suggest, is a common mechanism in a number of neurological disorders"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307240/
http://jop.sagepub.com/content/early...58732.abstract

Chronic anxiety and the pathways to disease
- abstract linking anxiety to increased pathways for inflammatory diseases:
http://www.citeulike.org/group/3317/article/6859282
-the complete text
http://www.telolab.org/uploads/3/1/0...l_bbi_2010.pdf

-Exercise and it's effects on:
Cytikines- any of several regulatory proteins, such as the interleukins and lymphokines, released by cells of the immune system and act as intercellular mediators in the generation of an immune response.
reducing
TNF - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation.

~To summarize: the relationship between depressive disorder, cytokines and exercise, epidemiological data shows the correlation between physical inactivity and low-grade inflammation [190-192]. Since immunotherapy reduces plasma levels of tryptophan, it is noteworthy that levels of tryptophan can be directly influenced by exercise. As already mentioned acute physical exercise increases blood free tryptophan and in animals [71-73] and humans [74-76]. And also IGF-1, which counteracts the behavioral depressing effects of cytokines [188], can be influenced by physical activity [60, 156].
from:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026330/

Omega-3 supplementation lowers inflammation and anxiety in medical students:
A randomized controlled trial
http://pni.osumc.edu/KG%20Publications%20(pdf)/211.pdf

Medications and their potentials:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995293/
http://www.ncbi.nlm.nih.gov/pubmed/22486246

*Studies on the role of glutamate and NMDA Antagonists- ketamine, mematine and amantadine
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439647/

- table including COX-2 inhibitors with references:
http://www.ncbi.nlm.nih.gov/pmc/arti...5293/table/T3/

Further resources:
http://www.wegenersgranulomatosis.ne...ory_Foods.html
http://eyestrain.sabhlokcity.com/201...ry-properties/
http://lib.bioinfo.pl/paper:16388933 -click on the clear tab (left side) to remove colors
http://www.naturalhealthresearch.org/nhri/?p=5008