Not sure if it's interesting for anyone here but I have come across some articles which look at the relationship between oxidative stress and anxiety. Here is one article:

Oxidative stress and anxiety

It's still a relatively new area that needs more research but it would be interesting to follow the news on current research in this area. It might lead to new (complementary) therapies for fibro/anx/depr sufferers.

From what I read so far, I learned that oxidative stress is linked to a number of diseases (alzheimer's, cancer). Researchers are now working on determining connections between oxidative stress and anxiety/depression/fibro. It has been suggested that oxidative stress contributes to their etiology. There are some contradictory findings, for instance when it comes to answering the question whether anxiety contributed to oxidative stress or vice versa. A Russian study concluded that, since anti anxiety meds reduced oxidative stress, it indicates that oxidative stress is not the cause, but a consequence of anxiety.

There have already been several studies to determine the usefulness of antioxidants in order to reverse oxidative stress and to boost immunity, as well as improve symptoms of anxiety & co.

In a study, patients suffering from anxiety disorders have reported a slight improvement of their symptoms after receiving 100mg vitamin B1 via intramuscular injection.

And here is a link to a journal which publishes original research in the area of cellular biology

Oxidative Medicine and Cellular Longevity — An Open Access Journal

In one of their researches by Masood et al., they concluded that in the brain, the expression of glutathione reductase 1 and glyoxalase 1 (involved in the antioxidative metabolism) is highly correlated
with anxiety-related phenotypes. Additionally studies on mice showed that the activity of these enzymes is highest in the most anxious
mice and lowest in the least anxious strains. Researchers were able to show that oxidative stress-related anxiety can be
reversed in mice upon inhibition of NADPH oxidase or phosphodiesterase-
2.

"We found that anxiety in mice is accompanied
by markedly elevated levels of ROS in neuronal and glial cells
within the cerebellum and hippocampus, as well as in neurons
of the cerebral cortex and in blood monocytes, granulocytes and
lymphocytes.As a consequence, we suggest that an
imbalance in the redox system of anxious mice plays a role in
neuroinflammation and neurodegeneration, predisposing them to
recurrent infection and chronic inflammation.
In agreement with our recent findings observed a significant relationship between trait anxiety and ROS
formation in monocytes of hypertensive(!) individuals."

[Travelinglady]

Thanks for sharing! I am always glad to see research trying to get at the actual biological factors related to disorders, with the hope that such factors can be prevented.

[kindachaotic]

I feel there is validity to this. Have read some info cause my mother has Alzheimer's.
She's had a stressful life. Tough childhood & emotionally abusive marriage.
Think that's a large reason her mind is going. Stress!