[JohnnyCash]

Hello.

This is my first post, so please excuse me if I'm not posting in the right category. I will try to do better with my future posts after I get familiar with the forums. I just discovered this forum board today and since my condition is kinda delicate, I posted in the general category.

My main concern right now is my new prescribed treatment involving Orfiril Long 1000mg. Although, any other advice will also be greatly appreciated.

General info:

I'm a 25 year old male from Romania. I suffer from severe depression and generalized anxiety since 2005 and ever since I have been following psychiatric treatment. Since 2008 until the beginning of 2015 I have taken Solian and Cipralex which helped me, but eventually lost its effects. After being hospitalized in a psychiatric hospital in April, my treatment was changed to Gabaran, Sertralin, Ketilept and Anxiar. Since it didn't help after more than a month of taking these, it was changed to Lyrica, Seroquel, Sertralin and Xanax (only if needed). Now I was prescribed Sertralin, Orfiril Long 1000 mg and Xanax.

* Solian (200 mg) and Cipralex
* Gabaran (300 mg, 1 morning-1 afternoon-2 at night), Sertralin (100mg 1-1-0), Ketilept (100 mg 0-0-1), Anxiar (1 mg 0-0-1 .. at night in case of insomnia and/or agitation)
* Lyrica (100 mg 1-0-1), Seroquel, Sertralin (100mg 1-1-0) - xanax ocassionally
* Sertralin (100 mg 1-1-0), Orfiril Long (1000 mg 0-0-1), Xanax (25 mg when needed)

For a short time I also took Triticco AC 150 mg.

After some gastroenterologic investigations, it turned out I suffer from hepatic steatosis (not related to alcohol). From what I have read, it seems Orfiril is not recommended for people suffering from hepatic problems.

After my hospitalization (April 10 2015) I was diagnosed with: Severe depressive episode without psychotic simptoms.

On the observation paper it is written: The patient (24 years old) cu psychiatric history, presents himself at the hospital with a simptomatology consisting in depressive disposition, generalized anxiety, severe mixted insomnia, amhedonia, decresed productivity, the simptomatology appearing aproximately 1 moth ago and progressing in psychostressful context.

(this is my own translation of what is written on the paper. from Romanian to English)

My depression/anxiety usually manifests itself with nausea and vomiting, tremor, among the usual simptoms of „fear” and „sadness”. These affected my life a lot.
My sleep is also interrupted every night, two or three times every night, even if I take strong sleeping pills. During the day I feel very tired, no matter how much I have slept during the night. My sleeping problems have been part of my „life” since I was a child.

Emotionally, I oscilate between „good” and „bad” moods very fast. Which, from my own knowledge, are symptoms of bipolar disorder (my mother also suffered from bipolar disorder, severe depression and insomnia... eventually she managed to solve it, and she has been „sleeping” since 2012).

The only thing that helps me recently is the Xanax, which I would describe as ‚the devil’s drug’, but it only helps me with panic attacks and generalized anxiety. It doesn’t have any sleeping effect anymore, not even after a 50mg doze. I really don’t want to get addicted to this (or probably I already got addicted).

My psychological problems (oficially diagnosed by psychiatrist/therapist and self-diagnosed)

Severe Depression with suicidal thoughts (officially diagnosed)
Generalized Anxiety Disorder (officially diagnosed)
Depersonalization and Derealization (officially diagnosed)
Obsessive Compulsive Disorder (self-diagnosed and recognised by several therapists)
Bipolar (self-diagnosed by recognised by several therapists)
Filofobia (self-diagnosed)
Phobias (dogs, bees, speed)(self-diagnosed and recognised by several therapists)
Jealousy (suspicions)(idem as above)
Attitude problems (lack of trust and others, and lack of self esteem)(idem as above)
Powerful emotions at conflict (tremor, nausea)
Powerful uncontrolled emotions (love)
Lack of motivation (i.e. job issues)
Insomnia (officially diagnosed)
Chronic fatique/tiredness (self-diagnosed)
Burnout Syndrome (self diagnosed but recognised by my therapist) – The Burnout Syndrome appeared two weeks ago and goes on to this day

General simptoms:

Physical manifestations (nausea, vomiting, tremor)
Feeling very hot, even when it is cold
Sweaty palms
Excessive sexuality
Fear of going mad (no wonder, huh?)
Fear in general
Dizziness and sensations of earthquakes
Derealisation and Depersonalization
Numbness of the tongue (and fear of swallowing it), of the fingers and of the arms
Very frequent dreams of Alien Invasion (this subject isn’t even a real interest)
Obsessions with plans, planning and plan solving
Lack of hope and very negative scenarios in my mind

Additional information:

• My grandmother, aunt and mother suffered from severe depression, anxiety and bipolar disorder.
• I don’t drink alcohol, don’t take drugs.. I don’t even drink carbonated soft drinks or coffee. I only drink frappe and smoke cigarretes.

A plea for help:

All I want is a normal, decent life. I want to be able to work, to have normal relationships and handle problems easier. I care a lot about my mind and I don’t want to ruin it with all this medicamentation. I need help. I know (authentic) therapy can’t be done via internet, but at least some advice would be very much appreciated. And of course, the answer to my main recent problem/dilema: Can I take Orfiril Long 1000 mg if I was diagnosed with hepatic steatosis? There are many ugly effects of this treatment that I have read about, and I’m not really sure if it’s a good idea to take it, considering that I’m alone at home most of the times and I’m not under professional supervision.

Thanks in advance

P.S.: I wrote this a bit quick, so there might be some grammatical errors and bad explanations, but it’s all that my mind can handle right now. I will provide more info if necessary.

Good day.

[Loss4wards]

I would consider speaking to your doctor about maybe choosing a different medication in place of the Orfiril, something that is maybe safer considering your health concerns.

I understand it's not always so simple, I've had doctors insist that a medication was right for me even though they were mixing it with other medications they shouldn't have. It resulted in worse hallucinations than I'd been having before. Unfortunately it took a full psychotic break for the doctor to accept that those meds shouldn't have been used together. Hopefully your doc will be more receptive to your input, and maybe prevent complications involving your liver.

[JohnnyCash]

Originally Posted by Loss4wards

I would consider speaking to your doctor about maybe choosing a different medication in place of the Orfiril, something that is maybe safer considering your health concerns.

I understand it's not always so simple, I've had doctors insist that a medication was right for me even though they were mixing it with other medications they shouldn't have. It resulted in worse hallucinations than I'd been having before. Unfortunately it took a full psychotic break for the doctor to accept that those meds shouldn't have been used together. Hopefully your doc will be more receptive to your input, and maybe prevent complications involving your liver.

Yes, hopefully, although I plan going to another doctor. This one couldn't help me at all in 5 months..

[Loss4wards]

A new doctor with different insights might do the trick Even if it's just going to a different doctor for a second opinion, he may be more willing to listen and act on your concerns. I think too many doctors are quick to just write a prescription and rush the patient on rather than really listening an understanding all the concerns of the patient.
I wish you good luck, Mr. Man in Black :P p.m. me if you ever want to chat.