[sun_flower]

I've been on 150mg. of Effexor XR for 3 years now. But I've been having more frequent depressive episodes lately. I tell her about them each time I go, and she wanted to up my meds a while back, but i was reluctant to let her.
But today I asked her to up my medicine. I really hate having to even take medicine, but I guess I need it.

I know everyone responds to meds differently. But if any of you were on 150mg. of Effexor XR and bumped up to 225 mg. how long did it take until you felt "better." I hope I feel better soon. I'm sick of feeling blah.

[splitimage]

150 mg of Effexor didn't do much for me except get me out of the really deep fog of depression. It wasn't until I got to 225 mg that I began to really feel better. It's been awile now since I started on it so I don't remember exactly but I seem to remember noticing an improvement in about 3 weeks. 225 mg is considered the therapeutic dose for most people. It's at 225 mg that the effect on norephinephrine kicks in to augment the SSRI properties, so 225 seems to be an optimal dose for a lot of people. Personally I'm on 375 mg a day which freaks out my pharmacist but works for me.

--splitimage

[sun_flower]

Originally Posted by splitimage

150 mg of Effexor didn't do much for me except get me out of the really deep fog of depression. It wasn't until I got to 225 mg that I began to really feel better. It's been awile now since I started on it so I don't remember exactly but I seem to remember noticing an improvement in about 3 weeks. 225 mg is considered the therapeutic dose for most people. It's at 225 mg that the effect on norephinephrine kicks in to augment the SSRI properties, so 225 seems to be an optimal dose for a lot of people. Personally I'm on 375 mg a day which freaks out my pharmacist but works for me.

--splitimage

Thanks for your input. I am hopeful that I will feel better.
I'm glad that 375mg a day works for you.

Since you are already on effexor, you'll probably see a difference fairly soon as it won't take as long to build up in your system. I was on 300mg for about a year. Good luck to you.