[sugahorse1]

I realised this morning that there really is not a lot of info out there about which drugs NOT to take simultaneously, as they interact negatively.
I've also recently learnt that cigarettes can affect the efficiency of some AD! Unless you have a doctor's degree and understand the intricacies of the workings of specific drugs, we need to be so careful about what cocktail of drugs we take.

Last night I had a serious migrane, which is not too common for me. I couldn't bear it, so I took an anti-infammatory (Cataflam D) as I thought it was caused by a tension in my shoulder/neck. When that didn't help, I took a Myprodol, which is effectively a mixture of codeine, ibuprofen and one other. Both of these are available over the counter in South Africa.

Well, I have woken up so nauseous and weak - I can't even keep liquids down and please do not suggest trying to eat anything.

Sure, it could be caused by a number of things, but I've done a bit of research, and it's interesting to see the info available - as long as you have time to decipher it!

I am on Edronax Reboxetine in the mornings and at night I take Epilim (Sodium Valporate) and a Benzo to sleep.
I have a feeling there has been a bad reaction here somewhere...

[splitimage]

I find making my pharmacist my best friend is a good strategy - they're way more educated than doc's on meds and interactions. I talk to my pharmacist before taking anything new, even over the counter stuff - better to be safe than sorry.

There are also some decent meds interactions checkers on-line. Sorry I can't think of the URL of the one I use off the top of my head, but they can be a good source of info as well.

--splitimage

Pharmacists can find all that information for you.

[feddy]

Here's a great url that I use all the time...

http://www.drugs.com/drug_interactions.php

I find all of the interactions so confusing and this website really helps me.

Good luck!

[Yoda]

It may have been an additive effect rather than an interaction.

Cataflam and ibuprofen are both NSAIDs (non-steroidal anti-inflammatory drugs). NSAIDs can cause stomach upset and it is advised to take food with them. Since both drugs are in the same drug class you might do better to take them alternately rather than both on the same day. Ask your prescriber for more information.

wholehealthmd.com has a reference library that is great for checking med interactions with other meds, over-the-counter drugs, and herbs & supplements. it's an american site but hopefully helpful for you.

[sugahorse1]

Thanks all. Ended up taking 1/2 day sick leave on Monday - was getting worried about dehydration, and really was no use in the office. Climbed into bed and snoozed. Then I started with flu-like symptoms, aching muscles, sore joints, fatigue... Just took it easy, wrapped up warmly and went to sleep early. Tuesday I felt much better, just needed to get my energy levels back up and try eat something decent.

I phoned my p-doc and she could also not recall there being any known interactions.

I did take the one anti-inflammatory about 1/2 an hour before the other - I only took the other because I wasn't getting any relief. I took these at about 7:30PM, and had last eaten at 3PM - not sure if that covers "Take with food"?