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  #1  
Old May 17, 2014, 05:44 PM
ArtBen2014 ArtBen2014 is offline
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Hi everyone,

I recently increased my Zoloft dose and I'm super agitated. I can't sit still. Can't sleep. I feel like I'm going crazy. Has anyone else experienced this? If so, how long did it take for this side affect to subside?

Thanks for the help! Please please help!

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  #2  
Old May 17, 2014, 07:48 PM
Anonymous817219
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With citalapram. But different people experience different things. I would back off to your earlier dose for the weekend and call your doc on monday. S/he may change it or have you increase more slowly.

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  #3  
Old May 17, 2014, 08:03 PM
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Sounds like it may have triggered hypomania. What is your diagnosis?

Fetzima for me triggered hypomania that lasted two months. I didn't get the agitation and no sleep with it though. Throughout the middle of the day felt wired and couldn't sit still. Could never shut my mind off. Mine was not unbearable. I didn't particularly like it but I could deal with it.
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  #4  
Old May 17, 2014, 09:07 PM
Anonymous817219
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Hypo mania isn't generally diagnosed until it has been at least four days. It usually includes creativity or elevated mood. If this started immediately after increasing the drug it is more likely too much serotonin. I hesitate to say syndrome because that implies something much more serious. I experienced this on citalopram and simply decreased the drug for a while until my body was used to a smaller dose. I'd hate to make more of this than it is.

I love sleep. I can't imagine dealing with that for weeks! Ugh!

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  #5  
Old May 17, 2014, 09:25 PM
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Quote:
Originally Posted by Michanne View Post
Hypo mania isn't generally diagnosed until it has been at least four days. It usually includes creativity or elevated mood. If this started immediately after increasing the drug it is more likely too much serotonin. I hesitate to say syndrome because that implies something much more serious. I experienced this on citalopram and simply decreased the drug for a while until my body was used to a smaller dose. I'd hate to make more of this than it is.

I love sleep. I can't imagine dealing with that for weeks! Ugh!
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No I was able to sleep for some reason. After dinner I would calm down which was odd. I love sleep too. Absolutely more than anything I love sleep.

I don't know if hypomania has to be elevated mood and creativity. It could be negative hypomania with agitation, irritability, etc. Mine was kind of mixed. Not really euphoric at all but not horrible either.

You are probably right though to early to tell in one day.
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The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #6  
Old May 17, 2014, 09:28 PM
Anonymous817219
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It's in the dsm.

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  #7  
Old May 17, 2014, 09:29 PM
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So it must be true.

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  #8  
Old May 17, 2014, 09:44 PM
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It so happens that PC has an article on it. As we were warned though we should not be making diagnosis. Pointing out possibilities I guess i would call it. It does say four days and only mentions irritability once.

Hypomanic Episode Symptoms | Psych Central

Call pdoc to advise.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
Thanks for this!
mgb46
  #9  
Old May 18, 2014, 08:14 AM
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I would not say agitation in itself is hypomania. Sounds it would be more anxiety related, maybe?
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  #10  
Old May 18, 2014, 10:19 AM
Anonymous817219
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If someone said they drank 10 cups of coffee and they are shaky we would blame the coffee, not the person's brain right? You'd say lay off the coffee. I think it is a matter if KISS. If lowering the dose doesn't work THEN it makes sense to talk other possibilities.

And I just mean until the op can speak to the doc.

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  #11  
Old May 18, 2014, 11:04 AM
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Quote:
I recently increased my Zoloft dose and I'm super agitated. I can't sit still. Can't sleep.
The OP lists three symptoms and doesn't say when exactly the increase took place. With coffee you would blame how the caffeine reacts in the brain, but of course you would say cut back on the coffee. If the Zoloft did trigger hypomania or some other set of side effects I think the doc would say cut back the dose and go up slower or not go up at all. You would still blame the drug and how it is reacting in the brain since they seem to coincide. Today is Monday so hopefully the OP can call the doc today. I am not disagreeing with your advice just pointing out the possibility of drug triggered hypomania.
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The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #12  
Old May 18, 2014, 11:48 AM
Anonymous817219
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Usually people mention two events in the same sentence when they think they may be related. I don't know why you insist on attaching a label to it. The op is agitated, can't sleep and can't sit. Those could also be the same symptom. It's not Monday. You had me nervous for a sec. But tomorrow is. Can't you leave the label to the doc for a sec? Reality is none of us know. I don't think leaps like that are appropriate or helpful.

ONE day. I can't believe this is a debate! Sheesh!

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  #13  
Old May 18, 2014, 12:37 PM
Anonymous100125
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OP - YES...I had an awful breakdown this past winter and was put on a high dose of Zoloft. I thought I was going completely, entirely insane. The agitation/anxiety sensation was UNBEARABLE. I felt completely crazy and could not help but tear at my cuticles, move my leg constantly until it was very sore (and still couldn't stop), I was an emotional mess. My p-doc described the experience I had as a "negative hypomania". Dropped the Zoloft dose down to 100mg (had been at 200mg). I'm at 100mg, but plan to drop it down to 75 or even 50. I really feel for you - what you've described is pure hell. Please contact your p-doc ASAP...imo, your Zoloft dose needs to go down. Best of luck to you~
  #14  
Old May 18, 2014, 01:11 PM
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Oh yeah today is Sunday. I was supposed to go to Buddha church with my daughter but she never got up.

They took away our thread so here we go again. We need to start another thread and not hijack this one. I dunno what topic and I am not starting it.

I merely pointed out the possibility of drug induced hypomania or as sister rags said negative hypomania. I don't know what the big deal about a label is. If that is what it is then that is what it is. If it is "side effects" that is still a label in a sense. Depression is a label. You can't really communicate without names and labels and commonly agreed upon definitions. Agitation is a label. I don't think I am insisting on attaching a label or making a leap. I pointed it out as a possibility based on my recent experience with Fetzima induced hypomania. I said may have and shared my experience.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #15  
Old May 18, 2014, 02:03 PM
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mgb46 mgb46 is offline
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I'm just finishing up my trial pack of Fetzima, ready to start the 80 mg tomorrow. Been feeling agitated and don't fall asleep easy. Any ideas of heat to expect from a higher dosage?

How are doing on Fetzima currently?

Quote:
Originally Posted by zinco14532323 View Post
Sounds like it may have triggered hypomania. What is your diagnosis?

Fetzima for me triggered hypomania that lasted two months. I didn't get the agitation and no sleep with it though. Throughout the middle of the day felt wired and couldn't sit still. Could never shut my mind off. Mine was not unbearable. I didn't particularly like it but I could deal with it.

Are you still taking it? How is it working for you?

Last edited by Wren_; May 18, 2014 at 07:14 PM. Reason: merged posts
  #16  
Old May 18, 2014, 02:11 PM
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jjm51 jjm51 is offline
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Quote:
Originally Posted by ArtBen2014 View Post
Hi everyone,

I recently increased my Zoloft dose and I'm super agitated. I can't sit still. Can't sleep. I feel like I'm going crazy. Has anyone else experienced this? If so, how long did it take for this side affect to subside?

Thanks for the help! Please please help!
yes. me too when i took zoloft.

sounds like 'akathisia.' truly sucks. it will pass/stop, but you need to talk w/your doc.

reduce, go up more slowly, or even try a different med. if you have a benzo available that will help you too.

i am super med sensitive. zoloft was the first psych drug i was put on. terrible doctor who never even told me about side-effects. just kept raising the dose. i lost about 20 pounds in a month. pacing, no sleep, really thought i was going crazy.

akathisia is pretty common among people that are med sensitive and starting/increasing a med. especially ssri's.

again, make sure to speak with your doctor.

hang-in there. again, it will pass/stop.
  #17  
Old May 18, 2014, 02:26 PM
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I had akathisia due to Halidol. I had it for months as they wouldn't take me off the halidol or switch and I didn't know enough at the time. They gave me Cogentin (a benzo) but it would have taken 10 times the dose they let me take to actually help it. I must have walked a thousand miles in 12 months. It was horrible. I didn't know SSRI's could cause it though only AAP's and AP's.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #18  
Old May 18, 2014, 02:54 PM
Anonymous817219
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Quote:
Originally Posted by zinco14532323 View Post
Oh yeah today is Sunday. I was supposed to go to Buddha church with my daughter but she never got up.

They took away our thread so here we go again. We need to start another thread and not hijack this one. I dunno what topic and I am not starting it.

I merely pointed out the possibility of drug induced hypomania or as sister rags said negative hypomania. I don't know what the big deal about a label is. If that is what it is then that is what it is. If it is "side effects" that is still a label in a sense. Depression is a label. You can't really communicate without names and labels and commonly agreed upon definitions. Agitation is a label. I don't think I am insisting on attaching a label or making a leap. I pointed it out as a possibility based on my recent experience with Fetzima induced hypomania. I said may have and shared my experience.

Yep. Labels can narrow your world but nope not going there.

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Thanks for this!
mgb46
  #19  
Old May 18, 2014, 03:33 PM
Anonymous817219
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Quote:
Originally Posted by zinco14532323 View Post
Oh yeah today is Sunday. I was supposed to go to Buddha church with my daughter but she never got up.

They took away our thread so here we go again. We need to start another thread and not hijack this one. I dunno what topic and I am not starting it.

I merely pointed out the possibility of drug induced hypomania or as sister rags said negative hypomania. I don't know what the big deal about a label is. If that is what it is then that is what it is. If it is "side effects" that is still a label in a sense. Depression is a label. You can't really communicate without names and labels and commonly agreed upon definitions. Agitation is a label. I don't think I am insisting on attaching a label or making a leap. I pointed it out as a possibility based on my recent experience with Fetzima induced hypomania. I said may have and shared my experience.

There you go…
http://forums.psychcentral.com/showthread.php?t=338079

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  #20  
Old May 18, 2014, 03:35 PM
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Originally Posted by Michanne View Post
Yep. Labels can narrow your world but nope not going there.
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I guess we can all go around experiencing the pure essence of everything but it would be impossible to communicate that experience without descriptions, names, and labels however limiting they may be to real experience. Might as well eliminate language science and all the rest.

Sorry I went there. Going to shut up now.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #21  
Old May 18, 2014, 04:49 PM
Anonymous100125
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Quote:
Originally Posted by zinco14532323 View Post
I had akathisia due to Halidol. I had it for months as they wouldn't take me off the halidol or switch and I didn't know enough at the time. They gave me Cogentin (a benzo) but it would have taken 10 times the dose they let me take to actually help it. I must have walked a thousand miles in 12 months. It was horrible. I didn't know SSRI's could cause it though only AAP's and AP's.
I hadn't known, either, that SSRI's could cause that awful feeling...yeah, could be akathesia, although the descriptions of akathesia I've read discuss physical symptoms and don't seem to include the terrible emotional feelings of agitation/anxiety.

Anyway, apparently AD's and probably a lot of other meds can cause the awful thing.
  #22  
Old May 18, 2014, 05:02 PM
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For me akathisia (a label) was not really emotional at all. No agitation. It was very ridged muscles and an inability to sit still. I had to keep moving to relax my muscles at all. Up all hours of the night pacing the block. Try that for 12 months. I don't even know how much the halidol helped with the psychosis. I wish I had been better at self advocating at the time.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #23  
Old May 18, 2014, 08:20 PM
Anonymous100125
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Okay, then it does sound like the "thing" I've described (and what the OP referred to) was not akathesia, because it wasn't purely physical. In fact, it was more emotionally-driven than it was physical. The anxiety-amped-up-to-SEVERE-agitation was pure TORTURE. The physical movements came form feeling so wired...a very, very negative feeling of "wired".
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