[silentangel1969]

When should I start noticing if seroquel is working or not? I'm at 300 mg at night (day 5) and in 4 more days I am to switch to 300 mg seroquel (regular). I have major depression, dependent personality disorder coupled with borderline personality disorder, and adult ADD.

[jelly-bean]

It usually takes longer than just a few days for a med to really start working. I would give it another couple of weeks.

I took Seroquel 200 mg XR (and an additional separate 50mg at night to sleep) and it didn't do anything for two weeks.. then I hit my head, hard, and it made my head go quiet at once. However that only lasted for two weeks - Pdoc and I disagree on whether it was the concussion or the med that was the cause. (Pdoc says med, I say concussion. Primary care physician agrees I had a concussion, he just doesn't know whether the going away of my psychoticy symptoms was a result of the meds or the concussion)

I took the seroquel for MDD (major depression) as well as being almost psychotic (it doesn't have a one-on-one translation in English). Basically I hear voices and see things, but as I'm quite aware they're not real, they're merely annoying, not worrying.

A few weeks after they stopped working the pdoc upped the dose to 300 mg XR (also with a 50mg add-on for sleep) which didn't do anything at all, so after a few weeks we quit that, too.