[pretty-eyes]

I've been on Cymbalta for a few months now and I've been slowly creeping back into extreme depression, worse than it has been in almost a year. Has anyone else had this problem?

[LonesomeTonight]

Originally Posted by pretty-eyes

I've been on Cymbalta for a few months now and I've been slowly creeping back into extreme depression, worse than it has been in almost a year. Has anyone else had this problem?

Cymbalta had a negative effect on me psychologically as well. I had to stop taking it because it worsened my depression

Possible trigger:

and I ended up self-harming while on it, which is something I hadn't done in many years

.

Definitely tell your p-doc--you might need to switch medications.

[bolair811]

I also had a negative response to Cymbalta. In fact, both times I tried taking it, I ended up in the psych hospital with severe suicidal thoughts.

[vonmoxie]

Made me much worse. SSRI's don't do much for me, but an SNRI like Cymbalta (and especially Cymbalta) has absolutely made things worse for me. I felt so much better when I stopped taking it, but full disclosure -- it took ages for it to get totally out of my system, and for it to even be possible to get undone the damage it did, which I'm still working on. Still though, I'm so much better equipped for life without it than I was with.

I have major depressive disorder comorbid with PTSD, which I doubt messing with norepinephrine much helps.. nor any other comorbid stress or anxiety disorder, in my opinion.

Besides seeming to deepen my depression, I also noticed that my self-care really worsened while on it, i.e. caring about bathing. They don't list this as a possible side effect but I think they know about it, because it is prescribed off-label for OCD. I suspect there are many secrets like that which never make it to the information insert.