[convalescence]

As of right now I am taking 15mg of Remeron & it pooped out months ago. I honestly don't know why I continue to take it. I asked my pdoc for a tapering schedule to switch to Amitrip, but I just started taking Amitrip with the Remeron under my primary doctors supervision. Amitrip made my chest hurt, made me euphoric, thoughts ran like crazy, and it was just amazing. I stopped because of the chest pain though, because it's a serious side effect.

Now I need to taper off of Remeron, because I'm under a lot of stress and it has sent me into a depressive episode. I feel miserable and agitated. I want to lash out at everybody, but hold myself back somehow. What's the point?

So my problem is finding the antidepressant that is "the one." The antidepressant that has worked the best for me was an Effexor and Abilify combination, but the AP (funnily enough) made me worse.

I should add that I have been on all doses of Remeron. They all pooped out.

I need an antidepressant that won't exacerbate gastrointestinal problems (as I have "IBS"), and works on both anxiety and depression. Lower risk of sexual side effects is a must. I will stop treatment with that particular medication if that happens.

I honestly don't know what to try next... I just need suggestions to take to my pdoc.

And just so nobody asks, I have been on all dosages of Remeron. All of them worked for awhile, but all of them ended up pooping out.

[gayleggg]

I just changed off of Fetzima and Saphris which both worked well for me for about a year. Now he has changed me to Rexulti and Brintellix which seems to be working okay for now. But with me it seems like after a while they all quite working.

[convalescence]

Same with me, gayleggg! I'm starting to consider asking for a mood stabilizer since some of them can be used to stop you from going too high or too low. I have more of a problem with going too low than I do with going too high, but if antidepressants keep pooping out or making me crash then I consider it worth a shot.

[Kathryn01]

There are SO many medications out there, and it's hard to know what will work for you because everyone has such unique experiences. (That's why it's so important to have a great pdoc.)

The most successful antidepressants I've been on are Prozac and Lexapro. Eventually they both stopped working, but I had some good years on them. Now I'm on a variety of different things with the newest being Provigil. It's only been a few weeks so I don't know how to feel about it yet.

Good luck to you!

I recommend Lexapro (escitalopram). This medication is an SSRI.

I hope you feel better soon.