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Benzodiazepines- a summary by TicTacGo (sources below)
Long acting: -chlordiazepoxide (Librium) • Onset: intermediate (PO) • Peak: 2-4 hours • Half-life: 5-30 hours • Oral equivalent: 10 mg • Indication: anxiety -diazepam (Valium) • Onset: Rapid (PO/IV) • Peak: 1 hour (PO) • Half-life: 20-100 hours • Oral equivalent: 1 mg • Indication: anxiolytic -flurazepam (Dalmane) • Onset: Rapid • Peak: 0.5-2 hours • Half-life: 40-250 hours • Oral equivalent: 30 mg • Indication: hypnotic Intermediate acting: -alprazolam (Xanax) • Onset: intermediate • Peak: 0.7-16 hours • Half-life: 6-12 hours • Oral equivalent: 0.5 mg • Indication: anxiolytic -clonazepam (Klonopin/Rivotril) • Onset: intermediate (PO) • Peak: 1-4 hours • Half-life: 18-50 hours • Oral equivalent: 0.5 mg • Indication: anxiolytic, anticonvulsant -flunitrazepam (Rohypnol) • Onset: intermediate • Peak: within 2 hours • Half-life: 18-26 hours • Oral equivalent: 1 mg • Indication: hypnotic -lorazepam (Ativan) • Onset: intermediate (PO)/rapid (SL and IV) • Peak: 1-1.5 hours • Half-life: 10-20 hours • Oral equivalent: 1 mg • Indication: anxiolytic -oxazepam (Serax) • Onset: slow • Peak: 2-3 hours • Half-life: 4-15 hours • Oral equivalent: 20 mg • Indication: anxiolytic -temazepam (Restoril) • Onset: slow • Peak: 0.75-1.5 hours • Half-life: 8-22 hours • Oral equivalent: 20 mg • Indication: hypnotic Short acting: -midazolam (Versed) • Onset: rapid (IV) • Peak: 0.5-1 hour • Half-life: 1.4 hours • Oral equivalent: / (used as IV) • Indication: hypnotic -triazolam (Halcion) • Onset: intermediate • Peak: 0.75-2 hours • Half-life: 2 hours • Oral equivalent: 0.25 mg • Indication: hypnotic -Similar acting non-benzos -zaleplon (Sonata) • Onset: rapid • Peak: 1 hour • Half-life: 2 hours • Oral equivalent: 20 mg • Indication: hypnotic -zolpidem (Ambien) • Onset: rapid • Peak: 1 hour • Half-life: 2 hours • Oral equivalent: 20 mg • Indication: hypnotic -zopiclone (Zimovane) • Onset: rapid • Peak: 1.5-2 hours • Half-life: 5-6 hours • Oral equivalent: 15 mg • Indication: hypnotic -eszopiclone (Lunesta) • Onset: rapid • Peak: 1 hour • Half-life: 6 hours • Oral equivalent: 15 mg • Indication: hypnotic Source: benzo.org.uk : Benzodiazepine Equivalence Table
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