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#1
Oct 11, 2017, 08:39 AM
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One of my docs said I can take nortriptaline with my Prozac. I've been taking celexa 20 and Prozac 40 for quite some time now, on my own, trying to balance the sedative effects of celexa with energizing prozac. I'm at a lose of what to do because I fear this may be harmful, although I feel it's doing pretty well.
I'm considering going to only Prozac and taking l tryptophan at night or something along those lines. |
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#2
Oct 11, 2017, 10:28 AM
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I don't know except for maybe possible side effects. I suggest you talk to a pharmacist and let your doctor know what you have in mind.
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#3
Oct 11, 2017, 01:08 PM
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Are you talking to you pdoc about this? You seem to be tinkering around on your own a lot.
__________________
 Eat a live frog for breakfast every morning and nothing worse can happen to you that day! "Ask yourself whether the dream of heaven and greatness should be left waiting for us in our graves - or whether it should be ours here and now and on this earth.” Ayn Rand, Atlas Shrugged Bipolar type 2 rapid cycling DX 2013 - Seroquel 100 Celexa 20 mg Xanax .5 mg prn Modafanil 100 mg 
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#4
Oct 11, 2017, 06:17 PM
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Both combinations can have seriously major drug interactions...but since you doctor know you and your history best I would follow their recommendations.
I don't think you're wise to fiddle around on your own with this...these are very potent drugs with serious side effects when combined. Go to https://www.drugs.com/ and use the Interactions Checker at the top of the front page.
__________________
 Bipolar l/Rapid/Mixed/Depression/Anxiety Disorders lamotrigine 100mg 2x/day Vraylar 6mg 1x/day methylphenidate 10mg 3x/day bupropion XL 200mg 2x/day bupropion IR 174mg 1x/day buspirone 30mg 2x/day quetiapine 50mg 1x/day I'm 50 Shades of Bipolar and I have no safe word... |
 *Laurie*
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#5
Oct 11, 2017, 06:29 PM
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The main risk from taking 2 SSRI's is serotonin syndrome, Nortriptyline is usually considered less of a risk as it has more effect on norepinephrine than serotonin (still has some though).
I'd be cautious about taking tryptophan with a SSRI for the same reasons, particularly if it's 5HT. |
| *Laurie*, still_crazy
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#6
Oct 11, 2017, 10:16 PM
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Sometimes people do take 2 SSRI's, but I would be extremely careful doing so on your own because of the very real risk of serotonin syndrome. In addition, sometimes 2 SSRI's can have the effect of creating depression, rather than decreasing it.
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#7
Oct 12, 2017, 09:10 AM
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hi. just from what ive observed, when 2+ antidepressants are used in the same person, docs seem to use drugs from different classes. so...ssri+remeron, ssri+wellbutrin, ssri+certain tca drugs, ssri+provigil ("off label"), etc...not ssri+ssri, tca+tca, etc.
other options include: low dose lithium, buspar, old school stimulants (ritalin, focalin, an amphetamine), a tranquilizer/neuroleptic, an antiepileptic drug (lamictal, trileptal, etc.), and I think some people benefit from adding in straterra. hope this helps. |
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