Symbyax®
Generic Name: Olanzapine and fluoxetine HCl capsules oh-LAN-za-peen & floo-OX-e-teen HCI
Drug Class: Fluoxetine and Olanzapine | | Contents | Description | This medicine is a combination drug used to treat bipolar disorder. Your doctor may prescribe this medicine for other conditions as well.
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| | General Information | | This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. Top of page
| | Proper use of this medicine | Take this medicine exactly as directed. This medicine is taken orally once every evening. This medicine may be taken with food if stomach upset occurs.
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| | Missed Dose | Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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| | Storage | Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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| | Possible Side Effects | - All medicines may cause side effects in some patients. Serious side effects reported by patients treated with SYMBYAX follow below:
- Severe allergic reactions that cause hives, swelling of your face, eyes, mouth, or tongue, trouble breathing or a rash with fever and joint pain. Tell your doctor right away if you get these symptoms. Your doctor may stop SYMBYAX and prescribe medicines t
- Strokes and "mini-strokes" called transient ischemic attacks (TIAs). These are more common in elderly patients with dementia. As with other mental health drugs, SYMBYAX should be used with caution in elderly patients with dementia. SYMBYAX is not approved
- High blood sugar or diabetes. Patients who already have diabetes should have their blood sugar checked regularly during treatment with SYMBYAX. Patients at risk for diabetes (for example, those who are overweight or have a family history of diabetes) who
- Neuroleptic malignant syndrome (NMS). NMS is a rare, but life-threatening reaction to certain medicines for mental problems, including SYMBYAX. Stop taking SYMBYAX and call your doctor right away if you get any of the following symptoms of NMS, such as a
- Tardive dyskinesia. This is a condition caused by certain medicines for mental problems, including SYMBYAX. It causes body movements, mostly in your face or tongue, that keep happening and that you cannot control. It may start after you stop taking SYMBYA
- Low blood pressure. SYMBYAX may cause low blood pressure in some patients. Low blood pressure is more likely in patients who have heart problems, who have brain problems such as strokes, who take certain medicines, or who drink alcohol. Signs of low blood
- Seizures. SYMBYAX should be used cautiously in people who have had seizures in the past or who have conditions that increase their risk for seizures.
- Impaired judgment, thinking, and motor skills
- Trouble swallowing
- Abnormal bleeding. When SYMBYAX is used alone, and especially with certain other medicines that can increase bleeding risk (for example; ibuprofen or aspirin), your risk of bleeding can increase. If you notice increased or unusual bruising or other bleedi
- Low salt levels in the blood. SYMBYAX can cause a low salt level in the blood. Weakness, confusion, or trouble thinking can be caused by low salt levels in the blood. If you develop any of these symptoms, contact your doctor.
- Body temperature problems. SYMBYAX can cause problems in keeping your body temperature regular. Do not become overheated or dehydrated during hot weather or exercise, or when using a hot tub.
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| | Warnings/Precautions | - Tell your doctor if you are allergic to fluoxetine or olanzapine.
- Alcoholic beverages can increase the effects of this medicine and should be avoided.
- Do not get over-heated or dehydrated (loss of body fluids) while taking this medicine.
- Do not take a MAOI medicine for at least 5 weeks after stopping this medicine.
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| | Overdose | Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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| | Drug Interactions | - Before taking any prescription or over-the-counter medications, supplements, or herbal products with this medicine, talk to your doctor about possible interactions.
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| | Pregnancy/Nursing | Before taking this medicine, if you are pregnant, breastfeeding or planning to become pregnant, talk to your health care provider. This medicine is not recommended for nursing mothers.
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| | More Information | For more information about this medicine, talk to your healthcare provider.
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| Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com | This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.
Last reviewed:
On 8 Aug 2006
By John M. Grohol, Psy.D.
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