SSRI induced mania/psychosis. Have you had it?

Have you ever been thrown into a severe manic episode because of an antidepressant like Prozac? What about psychosis? Were you on a mood stabilizer at the time? How certain are you that the ssri caused it and not something else? How bad was your psychosis/mania and how long did it last?

For me, I took Prozac and became severely manic, which led to a lot of bad things, and ended in a 10/10 worse psychosis ever. Lasted 3 weeks and I ended up in jail, with essentially full blown schizophrenia for the time being. I've never had psychosis before that, and am completely fine now that I'm off it and on lithium. Stress was also a big factor. Being manic lead me to do mushrooms which probably had an impact. I was smoking weed daily as well, but I had already been doing that for the previous 5 years with no problems until I started taking Prozac, yet the doctors still insist it was "cannabis induced psychosis" and had nothing to do with the Prozac.....

Celexa sent me into a mixed state twice, even though I was also in abilify. Prozac sent me soaring into mania, which degenerated into psychosis and ended with an inpatient stay after a severe self harm incident. That was partially my fault bc I refused to take a mood stabilizer because I wanted the mania.

The diagnosis is substance induced mood disorder or substance-/medication-induced BP (depending on DSM), so I wouldn't worry too much about what they think.

That they made explicit the medication bit in the name of the new diagnosis and they changed it to BP is a reflection of a growing understanding that serotonergic drugs (like fluoxetine) may cause mania.

I never had the misfortune of being exposed to SSRIs. I did however use 5-HTP, which is a serotonin precursor, which (probably) caused a mild mixed state (starting with mania).

I can't take antidepressants for the most part because of SSRI-induced hypomania. It's unfortunate, too, because of my OCD. But it's okay. I'm still doing fine. I think my pdoc would only prescribe me an antidepressant if I ever dipped down into a deep depression, which is not really my usual mood tendency. I lean more towards hypomania and mixed states.

I've had what I now know to be mania induced from SSRI's a few times. At the time, I didn't know I was manic, just thought I was cured. I ran around doing crazy things with my mouth flapping away with rapid speech but had no idea it was mania or bad. I thought the depression was gone and I was happy. Paxil and welbutrin both did this. Prozac had me manic and angry and I told my doctor but this was when it first hit the market and doctors didn't know manic response could happen from SSRI's or at least my doc didn't know. No psychosis from SSRI's that I'm aware of..... I do that part all on my own I guess.

I'm so sorry all that happened to you. I bet your doctor didn't even warn you when he prescribed the meds. They should tell everyone who takes these meds to be watchful. That would be the responsible way to prescribe. Big hugs to you.

I have gone manic from zoloft once, wellbutrin twice, (the second time I was on lamictal too, just wasn't strong enough to keep me stable)...paxil without a mood stabilizer pushed me into a manic state (before my diagnosis, but led to my eventual diagnosis, I had two manic and two depressed episodes in one year) and then a new pdoc added prozac to the effexor I was already taking and I soared into the sky (then went mixed, oh my gosh)...that was the year I went to the hospital for the first time ever. effexor was the only snri that I was ever able to take, along with a mood stabilizer, that kept me ok. I have had SO many med changes over the years depending on what mood I end up in, I typically had two episodes a year for several years. I"m prescribed pristiq now but am trying to get my meds back under control...I was not taking them for about 2 months. and no, not for any good reason, I was just being lazy and stubborn.

In retrospect my worst manias occurred when I was on Zoloft. I didn't know I was bipolar and my primary care doc kept putting me on antidepressants and I'd often quit taking them during or after what I realize how was a manic episode. Most recently an ER psychiatrist took my off of Cymbalta and believes it had a hand in kicking off my current mania.

not an ssri but remeron did it to me

The only AD I've been on is sertraline. It made me pleasantly hypo/manic for a few days, than made me crash for a few days. Up and down and up and down. It was awful. I ended up in the hospital. No psychosis though.

Before I was diagnosed (and had seen a pdoc) Wellbutrin sent me into a very fun hypomania until I started seeing things. It was prescribed under a different name (can't remember which) by my PCP for smoking cessation.

I'm on lithium and Wellbutrin now and it seems to be a really good combo. Prozac is where the danger was. It's good to hear that others have had similar experiences so that I can relate.

Long story short, yes, in March 2012 from Effexor, and even after reporting my symptoms to and getting yelled at by one psychiatrist, and dx'ed schizo-affective by another (not my current diagnosis), I stayed on it from Aug 2010 until Dec 2012. And I believe the psychosis lasted longer than and of the (hypo)mania/mixed episodes or depressions did, as I believe I was in untreated psychotic States off And on from I think Feb 2012, into early 2013. Yeah...

Oh and I was in welbutrin from November of last year until Feb of this year, after trying to trying to kill myself in January after I crashed down from a hypomanic episode. Now I'm not allowed on any antidepressant meds.

I was on a lot of SSRIs and tricyclics until my pdoc decided to put me on Lamictal instead. I don't know how many times I was manic. The last time some idiot put me on an SSRI thought I should be treated for borderline instead. I ended up with no sleep and sweating at all hours of the day and night. Thankfully I got another pdoc who read my chart.

My GP misdiagnosed me with major depression and we tried SSRIs with no mood stabilizer

I became very manic on both Zoloft and Wellbutrin with risky decision making, not sleeping at all, felt "invincible," increased drinking, difficulties keeping up with my thoughts, and eventually some psychotic symptoms. Anxiety got severe too, and it turned into a nasty mixed manic episode. I thought people were doing things behind my back and that I was being investigated at work. Sometimes episodes on Zoloft were rapid cycling....but then eventually, it would turn into a long, drawn-out dysphoric mania that would last for about 1-2 months. I took a little bit of time after work during one episode, and during another, I wasn't functioning well at work at all.

Also, I got speeding tickets was getting extremely hypervigilant: looking over my shoulder, making copies of keys as a result of some paranoid thinking, getting strange ideas in my head, even some OCD checking behaviors, and my thoughts would race from one thing to another to the point where I was shaking and losing weight. Even with Zoloft in combination with a mood stabilizer to help prevent the mania, I still had a manic episode. I knew Zoloft contributed, because as soon as that was added to my mood stabilizer to try to clear up depression (pdoc was reluctant, but said try it since she did not know what else to do for my depression at the time), I was completely manic within only a couple days. She did warn me ahead of time that it might not be good for me and that I should stop if I felt I was starting to feel "elevated," but it was too little, too late at that point. I will never again take any antidepressants.

Short answer, yes. Even trazodone causes a mixed and some of them cause mania. I don't doubt that your mania cause thinking impairment that lead to the shooms.

I became manic after taking lexapro. I received treatment swiftly with anti-psychotics, so the mania was fairly mild. I had some psychotic symptoms: visual hallucinations and paranoia.

Zoloft made me very angry, aggressive, and impulsive. Totally out of character for me. Now I know I was hypomanic and mixed.

Lexapro made me coconutzo.


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i am not bipolar but i have had psychosis from anti-depressants

My first full blown manic/psychotic breakdown with 1st dx was from a hormonal birth control shot.
Then after that I took myself off all meds and was manic but somehow got put on paxil which led to psychosis.
then while in a skin picking mood was put on prozac when I said no that I wanted something for OCD instead. pdoc just said prozac would work great and then I went manic with some psychosis, delusional thoughts and paranoia.
lately I was put on trazadone and had some manic behavior from that.
I can't take antidepressants!
bizi
bp1

I was recently told by my pdoc that Trazadone can cause mania, so she won't put me on it. I find it interesting though that it still seems to be prescribed to people who have Bipolar, but I'm guessing it only causes mania in some of us? And it probably isn't as likely to induce mania compared to the SSRI's like prozac and zoloft? Not sure, but I can't take antidepressants either! It seems it's hard to treat depression in those of us with bipolar when it comes to medication choices. When I'm depressed without any mixed mania, I feel it's hard to find anything that works. Even Lamictal doesn't seem to do much for the depression, although it does prevent me from crying as much. I wish I can find something that worked better for the depression without going manic or hypomanic on meds that set it off.