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  #26  
Old Nov 07, 2017, 10:13 PM
glennk glennk is offline
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Quote:
Originally Posted by CaminoDeOro View Post
OP here, I've definitely settled in to a 5-7 day ultrarapid cycle with periods of high instability. Trying to get my pdoc appointment moved up but it's next week anyway. My life is quite disrupted right now, I should have a relatively chill period between November 10 and December 15 or so if no additional random BS happens, so I guess we'll have to see if whatever the pdoc and I change, works, during that period, because after that I'm probably going to be traveling for a few weeks to avoid a toxic situation around the holidays where I live. It's better for my mental health to crash on friends' couches (as I am doing right now, one of the toxic elements also scheduled a visit for Halloween) than stay where I live during that time. But I am REALLY not looking forward to having med flux during that so hopefully we find something that is better at this next appointment. Otherwise maybe I'll go back on zyprexa - AGAIN - for a month or two because at least it keeps me stable, even though it does nothing for the depression. Being around my friends I haven't seen in 5 years will probably keep me from getting too depressed during that month.
How many atypicals have you tried?

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  #27  
Old Nov 12, 2017, 01:27 PM
CaminoDeOro CaminoDeOro is offline
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Thanks ~Christina. glennk, I have tried zyprexa, abilify, geodon, and seroquel. We are holding off on latuda for now due to the extreme expense and likelihood that I would have to discontinue it if I lose Medicaid for any reason.

I did get in to the pdoc, we have decided to be aggressive since I may have lower life disruption for the coming 5 weeks. So, I am staying on seroquel, coming off lamictal, and then adding pristiq. This is gonna be a white knuckle ride I think. There are sound reasons behind this but it's still a gamble, basically hoping to raise my baseline mood further so that I get more stuff done and go out more, since THAT improves my stability more effectively than meds, if it's maintained.
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Bipolar II ultrarapid cycling + ADHD-PI, both treatment resistant af
zyprexa 2.5 / dexedrine 10 / valium 3 :: CYP2D6 poor metabolizer
currently trialing meds one by one with a great pdoc after 20 years of fail
  #28  
Old Nov 12, 2017, 04:14 PM
Wonderfalls Wonderfalls is offline
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Seroquel at 100mg functions as an antihistamine (like Benedryl) even if you're a slow metabolizer. So it makes you sleepy and fights allergies. To get it to work as an antipsychotic you need to be on something like 300 or, better, 400mg or more. It's not known for causing akathisia and at 100mg shouldn't even give you its famous killer appetite. At an AAP dose it gave me terrible muscle and joint pain--which I've never heard of anyone else getting. So any drug can cause any side effect it seems like.

To the poster who takes gabapentin and atavan for akathisia. Cogentin (benztropine) or even better propranolol (a systemic beta blocker) should help more. It also has the advantage that it's only one medicine instead of two and it avoids building up a tolerance to the Atavan.
  #29  
Old Nov 12, 2017, 04:18 PM
glennk glennk is offline
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Seroquel XR was my saving grace.

If Latuda's cost is an issue, there is a program through Sunovion that provides free medication. Your pdoc will have to help with this.
  #30  
Old Nov 13, 2017, 01:39 AM
CaminoDeOro CaminoDeOro is offline
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Low doses of seroquel are effective for me because I am a slow metabolizer. Same with a lot of other drugs. Zyprexa 2.5mg has considerable effects both good and bad for example.

I'm gonna see where the pdoc's instinct goes on this one, I had the same thought as her why to try pristiq, but I would have tried to get my mood more stable first, she hopes that if my baseline mood improves more, stability may follow.
__________________
Bipolar II ultrarapid cycling + ADHD-PI, both treatment resistant af
zyprexa 2.5 / dexedrine 10 / valium 3 :: CYP2D6 poor metabolizer
currently trialing meds one by one with a great pdoc after 20 years of fail
Thanks for this!
glennk
  #31  
Old Nov 21, 2017, 05:20 AM
glennk glennk is offline
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Member Since: Oct 2017
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Quote:
Originally Posted by CaminoDeOro View Post
Low doses of seroquel are effective for me because I am a slow metabolizer. Same with a lot of other drugs. Zyprexa 2.5mg has considerable effects both good and bad for example.

I'm gonna see where the pdoc's instinct goes on this one, I had the same thought as her why to try pristiq, but I would have tried to get my mood more stable first, she hopes that if my baseline mood improves more, stability may follow.

Have you tried the XR formulation of Seroquel?
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