[NolaMae]

My symptoms have gotten to the point where I think I may need to go on an antipsychotic again and because of a previous bout of tardive dyskenesia I’m terrified. Does anyone have any idea of which one would have the least risk of TD without causing massive weight gain? Abilify was the one I took before and that was the one that caused TD. Thanks.

Hi NolaMae. There is no way to know which med(s) would or wouldn't do what to you. You need to trust your psychiatrist and just try a new one, if that's what your doc wants. I have never had TD from any antipsychotic in the 15+ years taking various ones. The closest I came was a brief dystonia from Navane (thiothixene), which is a 1st generation antipsychotic, but many others have taken that and/or other 1st generations with no problems.

I think weight gain is also not a given. I know people who say that they gained lots of weight on Seroquel XR, but my weight gain on this med is fairly minimal. I think Zyprexa, Clozaril, Risperdal, and Invega are more notorious for that. I gained more weight on regular Seroquel than its XR version. Geodon and Navane were weight neutral for me.

Some antipsychotics gave me akathisia, others didn't or not for a long time after starting them. Risperdal and Invega increased my prolactin levels. No others did.

Seroquel XR has been the most side effect friendly antipsychotic for me so far. My psychiatrist says it has the reputation for not causing extrapyramidal symptoms (akathisia, dystonia, TD) as often as other antipsychotics.

[~Christina]

What symptoms are you struggling with ?

How’s your sleep ? Any changes recently ?

[Movingon69]

I'm sorry. What is TD? I'm on Saphris. I've had not bad side effects at all.

Originally Posted by NolaMae

My symptoms have gotten to the point where I think I may need to go on an antipsychotic again and because of a previous bout of tardive dyskenesia I’m terrified. Does anyone have any idea of which one would have the least risk of TD without causing massive weight gain? Abilify was the one I took before and that was the one that caused TD. Thanks.

You just have to try one and see. Even your doctor can’t predict for certain what your side effects will be. It is difficult, but you can control your weight on an antipsychotic. You have to monitor your intake closely, but it’s not a given that any drug will cause weight gain.

[Fuzzybear]

I haven’t been on many AP’s (only Seroquel) but from the (relatively small) amount of research I’ve done, I also think Seroquel is amongst the least likely to cause TD. (High prolactin is also a concern for me.. and I think Seroquel isn’t as “bad” as some AP’s for that. As for weight gain, it isn’t a given, as others have said .. (btw I’m also scared of AP’s). I’m sending positive vibes

[Wild Coyote]

I don't have anything to add.
I am sorry you are going through this. I hope whatever you decide to try will work out.
Keep us posted?

Wc

I think the protocol with anti-psychotics is for your doctor to monitor you closely starting with a small dose to see if you get any TD. As long as it's caught right away it's not permanent. That's my understanding, anyways. I'm on Seroquel and Risperdal without any TD but i have had significant weight gain which i am working on but it's very much a work-in-progress. Good luck and if you keep a careful eye out for TD i think you will be fine.

[Fuzzybear]

I agree that the doctor should monitor for any signs of TD... and any other significant side effects.
(The doctor who prescribed the Seroquel for me... ... I hope you have better luck