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Old Dec 24, 2024, 12:15 AM
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BeyondtheRainbow BeyondtheRainbow is offline
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I have been on metformin at 500 mg since about 6 months after starting clozaril. It helped me stop gaining weight although I didn't lose any. After reading this article I may ask if I can try increasing to 1000. But I thought it was interesting and maybe could help someone.

New Guidance Backs Metformin for Antipsychotic Weight Gain
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  #2  
Old Dec 24, 2024, 12:19 AM
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Nammu Nammu is offline
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Metformin caused me continuing digestive issues it’s not a medication to just use without caution. I’m on three stomach meds because of metformin.
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  #3  
Old Dec 24, 2024, 12:25 AM
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BeyondtheRainbow BeyondtheRainbow is offline
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@Nammu I'm sorry to hear that. I know it can cause diarrhea especially with the instant release kind but I didn't know it could cause major issues.


Thanks for the reminder that no med is a safe med.
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Bipolar 1, PTSD, GAD, OCD.
Clozapine 250 mg, Emsam 12 mg/day patch, topamax 25 mg, ,Gabapentin 1600 mg & 100-2 PRN,. 2.5 mg clonazepam., 75 mg Seroquel and 12.5 mg PRNx2 daily
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  #4  
Old Dec 24, 2024, 12:52 AM
Tart Cherry Jam Tart Cherry Jam is offline
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Thank you for posting, BeyondtheRainbow. I was on it on and off. No side effects and no positive effects. It was eventually Ozempic that helped. And I also changed to less metabolically harmful APs from Zyprexa. But I definitely think that Metformin should be tried and appreciate that now there is this new guidance following a Cochrane review. I hope it helps many patients.
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Lybalvi 10 mg
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Gabapentin 1500 mg+Vitamin B-complex (against extrapyramidal side effects)

Long-term side effects from medications, some of them discontinued:
- Hypothyroidism
- Obesity BMI ~ 38
  #5  
Old Dec 25, 2024, 11:58 PM
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raspberrytorte raspberrytorte is offline
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I'm on 2000mg of metformin daily. I'm not gaining, but I'm also not losing. I still have a big ***. I'm not sure if the metformin is helping me or not. Thanks for sharing the article BeyondtheRainbow. It was an interesting read.

Sorry to hear about your stomach troubles @Nammu.
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What if the diamond days are all gone, and
Who will I be when the Empire falls?
Wake up alone and I'll be forgotten." 😢 - sleep token
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