Genome Test Results...Born Hopeless :(

So I did the genotype swab test. Got my results back this week. It's not very explanatory. So I've been looking up each code individually trying to understand...and apparently getting a crash course in advanced BioGenetics as well!

Basically so far, from what I have been able to decipher...
I carry multiple genotype, phenotype, and important synaptic deletions/mutations.

The most problematic is that I have a deletion that makes me in able to produce or metabolize dopamine. 25%of all psych meds are inhibited of this particular genotype..including almost all antidepressants.
Generally then a direct substrate would be the way to go..but the main phenotype that lays on a different genome,that is responsible for the main uptake and absorption of any substance that could override my inability to create and metabolize dopamine is a mutated Ultra rapid Metabolizer...so what does this all mean?
The deleted genotype and enzymes require me to consume much higher than what would be considered safe dosage to be effective, but the mutated UM causes med sensitivity at the lowest possible dose and any even normal/ low dosage has high likely hood to cause serious- deadly plasma toxicity levels....
So yah....basically I'm screwed.
Intrestingly bc of another group of mutated geno/pheno/enzymes (which is most likely the cause of my ADHD..or at least somehow proves I actually have it??) Is the reason that my adhd meds have had an anti depressant effect on me for so long..but bc they do have some metabolization on the deleted path..they are gradually becoming more ineffective...which would be solvable if I were able to tolerate or benefit from ritalin or any of the methylphenidate meds..but they only cause me to feel like a zombie with migraines having a heart attack .....genetic reason thus far unknown.
I'm a hopeless mess.

Yikes on bikes... what an example of our own bodies working against us! I'm not all that horribly smart so to be honest I wasn't able to follow the exact explaination of the way your genomes have mutated, but consider this;

They say that evolution is just mutations in the gene pool that survive the years. Maybe you're the start of a whole new species?

In all seriousness though don't give up hope. Not being able to take antidepressants is bad, but that means now you've gotta get creative with your treatments.

Don't buy into all this unless you want to have no hope for any sort of a normal life. The body and brain and extremely complex, and just because something's going on doesn't mean your life is hopeless.

Why not seek out a good naturopath who specializes in orothomolecular medicine which simply means giving the body the nutrients it needs to function. You would be amazed at how much better off you could be by rebuilding your health.

I wonder if that's similar to the same kind of thing my mom has. She can't take antidepressants either because they make her worse. Her psych had her go in for genetic testing after they tried a series of meds for bipolar and every single one had deleterious effects, ranging from constant nausea to almost life-threatening skin reactions. Apparently they found there's something genetic that makes her truly unable to take a number of meds.

No idea if I have anything similar; I'd love genetic testing someday.

At least now you know - maybe this can help lead you to find other treatments?

Aww...

Being hopeless, you shed all the lesser hopes and now you know that you're crossing the rubicon. I'm really sorry about the test result, life comes with certain risks, my opinion is that you're more than a neurotransmitter, please believe in yourself and loved ones that you could get through all the obstacles that's ahead of you.

I was reading something about 'Smart Drug' abuse the other day, the unfairness of it all is quite disgusting. Thanks for the post, it feels like I've learned something.

I don't know a lot about this stuff, I'll admit... but I'm with you, and I'm listening

This seems to have closed some doors to treatment for you but hoping that armed with this knowledge the right doctor or therapist can steer you on to a better course of mental health for you. Good luck, wishing you well on your search for hope.

Life is an uphill battle, I suppose it's better to steer it like that.

Going downhill on the other hand takes a lot of skills. Gunning a brake and a gas pedal at the same time drifting down, it's just not safe, you're more likely to total the car.

The title saids, born hopeless, does the test really tell you that? If that's the only way you can look at the lab result, I say you're wildin'.

Everything is Everything.

So convinced that they might fall
Let's love ourselves and we can't fail
To make a better situation (better situation)
Tomorrow, our seeds will grow
All we need is dedication
Let me tell ya that

.......

Hopeless Miss, please do not led astray by only one truth, for all we know, you could be like a dark angel like Jessica. Don't mind this lame tv show reference, if you're really bummed out, play good musics, 'Uphill' -> 'Lauryn Hill', you ain't going down the hill rollin. Take care.