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  #1  
Old Dec 02, 2009, 02:17 AM
mum2four mum2four is offline
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I recently started have serious issues with energy after not long after exercise or swimming. I feel great before often during but after wards I crash, I dont understand why, I was so bad 3 days in a row after using the pool that on the 3rd I was so close to calling an ambulance but I managed to get to home JUST. The reconmended blood work I asked for a ECG(EKG) because I had never had on before to be sure about my palpitation, thats a different issue. The last fue night I have not slept much I've been in pain with restleg syndrome. I took pain meds and it barly helped the first night and the second night I took pain meds and sedative I managed to sleep deeply for 3 hours.
I was still in heaps of pain this morning after sitting for while after gym. I decided to go my new dr about it and was planing to ask for stranger pain meds cause the strongest over counter meds were not fully working and whats the point of takeing pain meds if they dont work fully or enough to get on with life. So I made an oppointment went the she her managed to tell her how I was feeling in detail. She said my test were all normal and there really did not seem to be anything she could do for me......I burst in tear for the first time eva in front of a dr with out running out of the room. I STILL managed to keep talking to her(but had taken a 1/4 of a sedative a hour before) I dont know if the crying made her realise I was not faking or if she had make it look like she was trying to help, but she ended up giving me what I thought at the time was stronger sleeping med but it turns out to be an anti D med another one on top of the one I've been using for 7y. It feels litle she saying it depression but telling me it to sleep like a placebo, I read up about it and it does say it used for insomnia, PTSD, IBS, other issues I suffer from and some I hopeing I dont but have many of the symptoms.
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Unapproved / Off-label Amitriptyline may be prescribed for other conditions such as insomnia, post-traumatic stress disorder (PTSD),[3] migraine, rebound headache, chronic pain, tinnitus, chronic cough, postherpetic neuralgia (persistent pain following a shingles attack), carpal tunnel syndrome (CTS), fibromyalgia, vulvodynia, interstitial cystitis, male chronic pelvic pain syndrome, irritable bowel syndrome (IBS), diabetic peripheral neuropathy, neurological pain, and painful paresthesias related to multiple sclerosis and at low doses as a prophylaxis (preventive) for patients with chronic migraines.[4] Typically lower dosages are required for pain modification of 10 to 50 mg daily.[1]
Amitriptyline in low doses is also sometimes prescribed to help ease the symptoms of chronic fatigue syndrome. It is thought to help combat symptoms of insomnia primarily, in addition to other selected symptoms of the affliction.
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I still cant get it out of my head that she mainly gave it to me for depression reasons.

How is a anti D going to help me sleep my 200mg of luvox barly helps me sleep and it has a sedative componant to it. She said that hopfull if I can sleep threw the night the symptoms will subside basicly and thats all I want I to feel normal or at least function more normal right now I almost feel like gekal and hide but with energy not mood. I swap suddenly and it unpreticable. I just want a dr will take me serious I not looking to pricked and poked and tested just for the attention that the last thing I want I hate getting attention.

I'm gona talk to my T about this on friday 4th dec, I hope he does not make me feel like a hyperconract cause I know I'm not I know this is not in my head. I know its not and if it is I think I'd rather be dead than continue to live this way.

i'm so angry as well cause I just happened see the guy who smashed his way in my house and started me on roller coaster road that I want to be off of NOW stop the ride I want OFF and I want OFF NOW. I was scared to see him the first time in while I walk away but the further I got from him the more I want to go back and scream at him.....how dare he get to relax and enjoy life while I suffer like this..........I'm lucky I was far away I got a really stronger erge to turn around and scream at him if had been in the shop I was in I think I would have made a sean for the first time eva in public.

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  #2  
Old Dec 02, 2009, 01:40 PM
Anonymous32910
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Elavil (amitriptylene) is an older antidepressant that is VERY sedating. It also has some properties that makes it helpful with some nerve pain. My husband used to take it for a combination of depression and neurological pain. It knocked him out cold.
Thanks for this!
mum2four
  #3  
Old Dec 02, 2009, 03:36 PM
theave theave is offline
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I have been taking amitriptyline since January and I agree with Farmergirl, it is very sedating. I was on 200mg for most of the time since January but am starting to reduce it now - it really knocks you out. To begin with I struggled to wake up in the morning but as long as I take it early enough in the evening I'm fine now. When I first started I was also given zopiclone and I really couldn't stay awake the next day.
Thanks for this!
mum2four
  #4  
Old Dec 02, 2009, 04:32 PM
mum2four mum2four is offline
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Thankyou for helping feel better about this new med, I did sleep prety good for the first time in 2 and half years. My partner even said I did not toss ot turn or wake easy to noise ect. I dont remember much happening last night at all, normally I wake up prety much knowing what people said or did or if the Tv was off I cant sleep once I know it off. I remember turning over, changing position, ajusting my pillows, you name it I proberly do it just to find a way to feel comfortable to sleep. I have showers, or use the toilet heap, use the computer to get tired, take sedatives, rock my self to sleep, tap my feet, count, but last night nothing I felt heavy eyes I layed down and I remember nothing much after that. I woke up once when my patner came to bed but fell asleep right away. I woke up one to use the toilet and decide to see how people were going in chat but I could have gone to sleep if I wanted to. I was not in chat any where near as long as most times. The whole time I was in chat I had hevay eyes that got heavier prety quick.

I still have nagging thoughts(might be OCD) that my new Dr thinks I'm hypercondract.
  #5  
Old Dec 02, 2009, 04:48 PM
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TayQuincy TayQuincy is offline
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A few months ago my rheumatologist put me on Elavil because I have chronic pain that keeps me up at night (I have inflammatory arthritis). It is often prescribed for that reason, so I wouldn't assume that your doctor is thinking you are just depressed. I take 50 mg at night before i go to bed and have not found it to be very sedating. I now am taking vicodin too and that helps but I wake up when it wears off so I know how frustrating it is to have issues with sleeping.
  #6  
Old Dec 02, 2009, 05:58 PM
mum2four mum2four is offline
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my Dr rang me this morning and told me not to take the amitriptyline any more, she realised it might interfear with my luvox. I could barly talk to her I wanted to cry. I cant NOT sleep properly any longer she gave me hope and is now taking it away, I willing to risk it I am just to sleep.....I felt more responcive this morning I did not have force my self to think about people were saying to me and then think about how to answer it. i need to feel better what am I going to do.
  #7  
Old Dec 02, 2009, 08:33 PM
theave theave is offline
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That's a nightmare, I am sorry you are in this position. Is the doctor you spoke to your psychiatrist or GP? If the latter, then maybe you could get in touch with your pdoc with their more specialised knowledge? I started taken bupropion (wellbutrin) while still on amitriptyline - that combination made seizures more likely but I was fine. I do really feel for you as lack of sleep has been a major part of depression for me and it has helped having had decent sleep this year. I was still very nervous about decreasing the amitriptyline as I really didn't want to give up just being able to sleep most nights. Take care of yourself.
  #8  
Old Dec 02, 2009, 08:36 PM
mum2four mum2four is offline
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I could go back to the phychiatrist that put me on zyprexa and see if hes willing to give me some thing that a little bit more off a risk like this med and monitor me..All I know is I dont want zyprexa as it what started this problem . and I slept so well last night I would love to keep on sleeping like that to see if it resolves the servity of the way i feel.
  #9  
Old Dec 02, 2009, 09:40 PM
theave theave is offline
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Maybe speaking to your psychiatrist would be the best thing to do. Sorry to be dense but are luvox and zyprexa both anti-depressants? I only know the generic names, not the brand name.
Hugs from:
Jolbjwueby
  #10  
Old Dec 02, 2009, 10:04 PM
mum2four mum2four is offline
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luvox is anti D SSRI and zyprexa anti phycotic.
Thanks for this!
theave
  #11  
Old Dec 02, 2009, 11:53 PM
mum2four mum2four is offline
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Do I take the new med tonight or do think its not a good idea. Dr did not say Absulotly DONT take the med she did not make me feel like it was dangerously fatal interaction. She said maybe not a good idea to take them due to posable interaction. I not sure what should do......it felt more like she was covering her bases by telling me she sujested using the nitrazapam to sleep rather than the amitriptyline.

You proberly wont feel like you answer this but I had to put these thoiughts down anyway. If you have an oppinion it would be nice but I dont want people thinking I'm looking for yes or no just oppinions maybe at least what you think.... If is was seriously dangouse she would have told me to absulotly never take them and thorw them away right. Technicly I should not being useing nitrazapam either as is a sedative might interact with my luvox but Iv been safly using that together for a while now and before the nitrazapam I use diazepam which was fine and had the posabilty of interaction worse than nitrazepam does.
  #12  
Old Dec 03, 2009, 05:42 AM
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phoenix47baby phoenix47baby is offline
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It sounds like this doctor who is prescribing does not fully understand the consequences of prescribing certain meds. It is a bit alarming that she is telling you that they may not mix well with certain meds. That is the reason for checking in with a psychiatrist who specializes in psychiatry and dispenses meds on a regular basis. I just wouldn't want to see you have an adverse reaction. I wouldn't take any of these new meds until I checked in with my psychiatrist or better yet a pharmacist who is required to fully understand the medications he/she dispenses. Good Luck!
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  #13  
Old Dec 03, 2009, 04:14 PM
mum2four mum2four is offline
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thank you for that I fully understand what your saying........I agree but I also know Australia has more wanings about possable medication interaction extra. Australia takes longer to approve new medication, we dont have all the medication that america has, and even the really old medication that american's say are old are still the most commen meds to be given to Australian's.......

Our warning system for medications is very high....what I find interesting is and confusing is that when reading about luvox my main medication I read that zyprexa and diazepam is more likly to interact with luvox. The main interaction being something to with the way your body matbilizes thr=em together what ever than being, I'v also read from other web pages that carbanazeepine might interact with luvox. Yet I have been precribe all 3 by different Dr's.
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Drug interactions

Fluvoxamine has a low potential for the drug interactions which are based on inhibition of enzyme Cytochrome P450 CYP2D6. Fluvoxamine shows the least interaction of the SSRIs, in regard to this specific enzyme.[21][22][23] Naturally the other SSRIs which are metabolized by CYP2D6 will have more CYP2D6-based interactions with TCAs, antiarrhythmics, B-blockers, phenytoin, opiates (eg. codeine, dextromethorphan, morphine, tramadol) and neuroleptics (eg. haloperidol, risperidone).
Fluvoxamine does, however, inhibit cytochrome P450 enzyme CYP1A2, which metabolises Agomelatine, caffeine, clozapine, haloperidol, phenacetin, tacrine, theophylline, and olanzapine. These substances can cause increased serum levels when administered together with fluvoxamine. Of major concern is the fact that the polycyclic aromatic hydrocarbons found in tobacco smoke are potent inducers of CYP1A2 so that smokers may require significant modification of medication dosage.[24] A recent warning has been published regarding potentially serious interaction with Tizanidine, based on CYP1A2 metabolism.[25]
Fluvoxamine inhibits metabolism of diazepam and phenytoin via CYP2C19 and inhibits metabolism of aripiprazole, chlorpromazine, clozapine, haloperidol, olanzapine, perphenazine, risperidone, thioridazine and zuclopenthixol via CYP2D6 as well as inhibiting metabolism of aripiprazole, clozapine, haloperidol, quetiapine, risperidone and ziprasidone via CYP3A4.[26]
The plasma protein binding of fluvoxamine is about 77%. Drugs with low protein binding are less likely to displace other protein bound drugs, and therefore have a lower potential to cause protein binding-related drug interactions.
Fluvoxamine also inhibits: CYP3A4, CYP2C9, and CYP2C19 [19] [27]

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I think in australia we have medication that CANT be mix EVA together and other medication that are negotable but require lots of monitoring by Drs to check for reaction, or changes. I think luvox is very suseptable to reduced effectiveness with other medication. Specially with caffine I cant drink caffine with out feeling like I have not taken my medication properly. If can take zyprexa, diazepam, carbamazeepine, at different times over the corse of using luvox than I dont see why I cant use amitriptyline now. In australia the warning are there to protect people and keep them at ther PECK health if the posiable side effect out way the problem that is causeing serious lack of quality of life then a Dr has to decide which is the better option living with the med of trying the med and watching for posable symtoms. I think I'm at my bracking point and after taking the med the first night with out the Dr knowing that there posible interaction I felt so great the next day I already felt so much better.....I'm hoping I get this Dr let me take it and I'll stop if anything negative happens.......I cant keep on trying to get threw my day the way I have been feeling and if insomnia is causeing these problem which I kinda feel in at part that is true, insomnia is making my symtoms worse, I've always had issues but I could tolerate them now I struggling to tolerate any thing cause it gotten to bad......I just want to sleep....I get more side effect from nitrazepam than I did from Amitriptyline......Notrazepam makes me apear drunk the next day mainly due to sluring of speach. I have to keep explaining it my medication. The night after amitriptyline I had no slured speach I felt heavey eyes but my partner was saying i was specking clear and I felt so alert but on to anxiety triggers alert and responcive in conversation I did not feel I had to concetrate on just keeping my self upright. I think the benifits out weight any risk of posiable interaction it may even mean i wont need nitrazepam much or at all if I can do things easier I should be able to control panic better.
  #14  
Old Dec 03, 2009, 04:38 PM
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Glad to hear that Australia has such a stringent medication system. It is good to know! Sending good thoughts today!
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  #15  
Old Dec 03, 2009, 07:18 PM
theave theave is offline
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Hope things will work out for you.
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