Antidepressants

My Pdoc is changing my meds- from wellbutrin to effexor or some other antidepressant because he thinks that it may be contributing to the voices and homicidal day dreams. I don't know if I really have anything to worry aobut but I'm just worried that I'm going to hit bottom. What ones have worked for anyone?

I'm not a good person to ask about AD's because I had to try a bunch of SSRI's before I figured out that these don't work for me. I'm now on an MAOI, Nardil, and it's working well.

I just wanted to mention that Wellbutrin affects dopamine in the brain, and an excess of dopamine has been linked to hallucinations. I know of a man who had to go off of Wellbutrin because it caused auditory hallucinations.

I hope you find an antidepressant that works well for you.

gg

With changing anything, make sure to watch out for any changes in you whatsoever. It can be a very dangerous time, and it's best to have accountability with someone you're around a lot, or make yourself be around someone who is aware of your situation. Personally, after going on Cymbalta(which is[was?] working well after the initial few days) and experiencing suicidal impulsivity and a resulting attempt, which I then decided wasn't a good idea and called for help; I don't think I'd be willing to try changing medicines outside of a hospital - I just don't believe I can trust myself with it. That may not be the case for you, and I don't want to scare you, but just reinforce that accountability is a good idea.

Also, Effexor is a strong med, as compared to simple SSRI's, it's in a different class (something like "dual-acting") along with Wellbutrin and Cymbalta because it affects more than just serotonin - they affect some combination of serotonin, dopamine, and/or norepinephrine. Since you worry about "hitting bottom" I wanted to make sure you're aware of the risks involved - but to even it out, most people don't have these problems. And it's well worth finding a good med, just make sure to keep yourself safe.

I'll tell you what works for me - a combination of Cymbalta, Lexapro, Eskalith, and Seroquel to counteract an insomnia side-effect - but these things are very different for everyone. It's a matter of finding the one(s) that works best with your body chemistry.

Thanks for the advice. I will make sure I'm safe. Another doc filling in for my other one decided to leave me on the wellbutrin and add remeron. So hopefully things will be getting better soon.

I started out on Paxil and I was a druling mess and came off of it. I began taking Effexor XR in December and currently still take it. It works well for me. All AD's are different and work differently on each individual. Good luck in finding the correct med.

Jen

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evildouble102 said:
Thanks for the advice. I will make sure I'm safe. Another doc filling in for my other one decided to leave me on the wellbutrin and add remeron. So hopefully things will be getting better soon.

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A word of caution about Remeron, it is extraordinarily sedating in the beginning. I would take as little as 7.5mg & work up slowly.

Most AD's don't work for me after over 9 years of trial and error. My last AD was Pxil CR, and it made me manic (at 75mg/day).

I'm currently on Lithium, Seroquel and Klonopin, and they are working wonders I never thought possible.

Dolfin