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Old Nov 27, 2006, 03:14 PM
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Does anyone take any cortisol blockers to help control levels of this stress hormone?

Wondering if this may be a good alternative to say, downer-type drugs like Clonaz, or valium, etc..
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  #2  
Old Nov 27, 2006, 04:21 PM
psisci psisci is offline
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Elevated cortisol is a complex biproduct of chronic stress, PTSD, depression etc, but not a cause. Look up "hypothalamic-pituitary-adrenal axis".

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Old Nov 27, 2006, 05:27 PM
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Would you know of any specific sites? Would you know if this is a viable alternative for someone who is med resistant?
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Old Nov 27, 2006, 06:07 PM
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I didn't even know such a drug existed! I so need a cortisol blocker!
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Old Nov 27, 2006, 08:47 PM
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They do not work, and even if they did would not reduce your symptoms in any way.

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Old Nov 27, 2006, 09:49 PM
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LOL but they might let me lose the weight! Cortisol Blockers
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  #7  
Old Nov 27, 2006, 11:05 PM
psisci psisci is offline
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naw...that is myth as well. If it really did reduce cortisol it would be by script only as cortisol is very important for many endocrine functions.

Dr.S.
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Old Nov 28, 2006, 08:58 AM
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Well, that means stress which increases cortisol production does not cause weight gain... what part of stress DOES cause the weight gain, if food intake remains the same? I don't want to block all of it, I need to block the over production.
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Old Nov 28, 2006, 06:06 PM
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Why not? If it blocks the stress hormone from entering one's system, then why wouldn't it reduce the effects that stress has on the body. And if it is available by "script," then what is its function? For what purposes would it be prescribed?

You also mention that it is important for endocrine function. Does that mean that coritsol is required to say, stress our endocrine system into working (for lack of a better way to state)?

If stress causes the overproduction of cortisol, which in turn causes other physical problems, then why would the blocking of (some of) it not help?

(I am not looking to lose weight, by the way)
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  #10  
Old Nov 28, 2006, 06:14 PM
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Hi...

To add to what Dr. S said...

I had PTSD and was on klonopin...my cortisol levels were still elevated after months on the drug (klonopin and the benzos are not "cortisol blockers" either)...

Chronic stress does affect the central nervous system - that's why people with PTSD have an exaggerated startle response (for example, they jump easily)...
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Old Nov 28, 2006, 07:30 PM
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Dr. S. is correct..........
  #12  
Old Nov 28, 2006, 07:41 PM
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The Mayo Dietician says that you do gain weight under heavy stress if you are not a healthy individual, because of the stress hormone cortisol. Since the "blockers" don't work... well what studies have been done to show they don't work? Cortisol Blockers This is disappointing indeed. Cortisol Blockers
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  #13  
Old Nov 28, 2006, 09:43 PM
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None that I am aware of, but that is because they are just supplements. If they really reduced cortisol they would be controlled by the FDA and be a script only. Cortisol is a natural steroid, like cortisone etc... It is very important for many functions, including keeping inflammation under control so we live, as well as many other functions. Cortisol can be elevated with chronic stress, PTSD, Depression, but that is not necessarily always the case. SSRI's are the only medications shown to reduce hypercortisolemia, but why they do that is very complex.

FYI, if these supplements claimed to treat fatness they would get in trouble, but they can claim to lower or raise anything without proof as per FDA guidelines.

Dr.S
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