MED fear

jimi, its not all about you buddy so they don't work for you????? you tried you it failed end off, you may be treatment resistant there are many that are. Don't call every med because they don't work for you, your angry and frustrated its not the meds fault.

KETAMINE will never be used for depression on mass. its already a class A drug in ENGLAND .

Seem to be getting away from the thread of scaring newbie med takers , NOW READ THIS FROM A MILD START UP SIDE EFFECT LEAFLET FOR LEXAPRO . SIDE EFFECTS: The most common side effects associated with escitalopram are agitation or restlessness, blurred vision, diarrhea, difficulty sleeping, drowsiness, dry mouth, fever, frequent urination, headache, indigestion, nausea, increased or decreased appetite, increased sweating, sexual difficulties (decreased sexual ability or desire, ejaculatory delay), taste alterations, tremor (shaking), and weight changes. Although changes in sexual desire, sexual performance, and sexual satisfaction often occur as a result of depression itself, they also may be a consequence of the drugs used to treat depression. In particular, about one in 11 men given escitalopram report difficulties ejaculating.
NOW IF YOU CARNT TAKE ANY OF THESE SIDE EFFECTS THAT ARE LABELED MILD, THEN DONT TAKE AN ANTIDEPRESSANT , YOU ARE NOT COMMITTED AND WILL FAIL.

So, a patient shouldn't even try an antidepressant on the chance they might experience a mild side effect? They have no idea ahead of time the degree of the mild side effect or if it will last two days or two months. It makes much more logical sense to most to give it a try and see whether they will even have side effects in the first place, and then if they do to see if they are tolerable or not.

It is completely unfair to label people as not committed if they have problems with side effects that become intolerable. It is very difficult to know ahead of time if a) you will even experience a given side effect, and b) whether the level of a side effect will be tolerable or not.

Ketamine is a controlled substance her too. Street drug called Special K. That doesn't mean the research won't lead to something.

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Yeah every ones biochem is so different that every experiences them differently. Very hard to know what will happen and how severe. That leaflet came from very limited clinical trials. Not a lot of people in them.

I do agree though that if you start a med you should commit to it and give it a fair shot. Chances are you will get over the side effect. However it might be intolerable. I couldn't handle Wellbutrin longer than two weeks. Thought I was doing meth.

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Sorry for hijacking your thread earlier. I will start a new one.

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The side effects are listed mild, that's what I am saying,. you may get none, but if you get what they call mild and you carnt hack it , why take them. The side effect warning is FOR MILD, if you are suffering from clinical depression your suffering far more than any mild side effect so I don't see why anyone should bail out. THERE LABELED FOR YOU TO SEE, so what is there to complain about . There not headache tablets where it goes away after 1 hour.

There is a continuum of these side effects though. Let's take drowsiness for instance. It is listed as a mild side effect. On one end of the mild sedative effect is simply feeling drowsy for a few hours perhaps after taking a med. On the other end (still considered mild) is drowsiness that may cause a person to be unable to drive safely. They won't label that kind of sedation as even moderate or severe; they still label it as mild. But this can be a real safety issue for some people. My depression is NOT more severe than having a wreck and endangering my life, the life of my children, or the lives of others.

How about this one: increased sweating. Sounds innocuous, right? But I've dealt with this "mild" side effect. For most people, sweating is sticky and inconvenient and a nuisance. However, I have bipolar disorder, and the side effect of increased sweating was causing me to wake up multiple times during the night and lose significant hours of sleep. Decreased sleep is a trigger for bipolar episodes which can become increasingly severe and debilitating. So, increased sweating can be much more than a sweating issue for some people and though labeled "mild", the consequences could be quite serious.

You can't generalize.

There is no real way to predict in advance what side effects you might encounter. The best you can do is try what is available, monitor any problems, and decide at that point if those side effects can be tolerated or if something else needs to be tried. Often there are other options.

I have to agree. One of the side effects I have from Celexa is daytime sleepiness. I was so tired all of the time and could have easily fallen asleep at the wheel had they not given me Ritalin to counter act that tiredness. The sad part is I thought I was a narcoleptic and they never tied my sleepiness to Celexa. It was only until I went off the Celexa for other reasons that I found out my tiredness was a side effect of the drug!

The way I was feeling was definitely severe, if it wasn't the sleep doctors would have never prescribed me a controlled substance.

Perhaps if they had labeled this side effect more clearly I wouldn't have been on Ritalin for 3 years. Then again it could be that all the sleep doctors I have seen are incompetent as they (3 different ones in two different states) were well aware I was taking Celexa.

All meds say if affected by tiredness don't drive, that's a no brainer to me. I just listed what the maker has put on the med label has MILD . lots are complaining of the listed mild effects , but there printed in black and white if you cannot stand the mild start up then don't take the med .I HAVE TERRIBLE START UPS , but it never crossed my mind to give up . I want to get relief but I no there is no free lunch with anything, 90% get worse before better , I am bipolar but wont take antiphycotics because they make me fat , nothing else just fat so I say no. Its not a mild start up affect its permanent that's a hole new ball game. MOST People starting AD, have a few weeks off work till the side effects subside .IF you can go to work you not suffering clinical depression, you don't no what year it is never mind the day , mild depression is another thing but me personally would not take an AD for such.

What you are failing to hear me say when you say "if you cannot stand the start up then don't take the med" is that the simple descriptors don't really mean anything when there can be such a variation in a single side effect. The effect can have a mild impact, or that "mild" side effect can have a huge impact depending on the individual's diagnosis or circumstances.

You seem to imply that you have to be willing to accept any of the mild side effects listed on a drug insert, no matter how disruptive or serious that "mild" effect may be, or you should not even try at all or, as you said earlier, you aren't committed to getting better. It really is the other way around. Most people are willing to try anything in the hope of getting better, even with potential side effects, and only after they have been on the med to find out if there are any side effects and if they are tolerable (which is variable) is a decision made about whether it is possible to continue on the med. Having to stop because of intolerable side effects does not make a person less committed to the improvement of their symptoms.

I know absolutely no one who can take "a few weeks off work till the side effects subside". And you can absolutely go to work while clinically depressed. I've done it many times. In fact, I've walked right out of work and gone directly to the hospital several times after I had fought like hell to get through several days or even weeks of work while clinically depressed. It wasn't fun or easy by any means, but I managed to work because I HAD to.

Not everything is as black and white as you seem to see it. Perhaps consider that there may be other experiences and perspectives than your own.

I have worked all my life till 59 the last break down was critical. But when in onset of clinical depression I could not move from my bed never mind work, what good would anyone be at work if near blind with depression. I have worked through depression when it lifts enough sure , but I would not be able to get to work never mind hold down a my job, we seem to suffer different levels I have never walked to hospital, I have been blue lighted a few times even off the building site. What pray tell is your answer to side effects then ,you give up the med is that what your saying and the next one and the next one , there isn't enough to do has you seem to recommend.

I will say again that the side effects listed in that pamphelet come from the initial clinical trials and are very limited. Only a couple thousand people if that.

What is much more important is the clinical data that comes in after a drug has been on the market for a long time. That is real life experience with millions of people. The side effects from the initial clinical trial are going to vary widely when it gets out into real life.

Ocourse and the same labels on 20 year old meds are not the same now. has when first printed , then Benzos were not deemed addictive , the labels in England are constantly upgraded. This is not MY THREAD now you made it your own with scare mongering on side effects, the very thing I was trying to put newbies at ease with. im done hear

I am not scare mongering or taking over your thread. Above is my first response totally agreeing with you. Chill out dude. The thread did get off on a tangent and I apologized and said I would start another thread which ChangingMyMind did.

If they update the pamphelets on a regular basis based on new data then I was wrong. I can admit that. How in the hell am I scare mongering. It is just a fact that side effects very widely from person to person. A newbie should not go in blind to this fact. They should make a commitment to stick it out and suffer through the mild side effects and give it a fair chance. I have agreed with you on that like three times in this thread.

So if everyone doesn't agree with you 100% you are going to pick up your marbles and go home? I have never seen you on these boards afraid to voice your opinion.

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I think the point is that to give a medication a truly fair trial, then what ever mild side effects you experience, try to wait out for a couple of weeks. Now, if fatigue is noted as a mild side effect, yet it makes you so exhausted you can't drive, then for you, it is not a mild side effect, it is a major one. A minor SE for one may be debilitating for another, so you need to use your own judgement and make your decision from there. If a symptom is listed as mild it's simply because that is how the majority of the participants in the trials experienced it. So you have to be the best judge and decide if you can stick out the side effects that are mild to you. Prozac made me really nauseous at first, but I stuck it out and it subsided. But if it were my husband, he'd be in bed for a week and would have never taken it again.

We don't even have severity listed, only "very common", "common", "rare" and "very rare". Had a doc that tried to stop me from reading the list because she told me I would sabotage my treatment by getting everything I read about... Sigh. She didn't get some stuff I can deal with, some I cannot tolerate and might be dangerous for my other illness. Being totally in the dark about side effects I don't think is a good idea. I have never managed to get all the side effects I read about. Is it even possible?

Being tired is not ok for me either. My job involves a lot of mental concentration. I'm sure being tired was a problem at my last job. I wouldn't say it cost it but it was a contributing factor. If I had a job that doesn't involve so much concentration I might be able to work through it. As it is I couldn't tell what was the depression and what was the med (most likely a mix of both). I tried tolerating it way too long as a result. And really, parents with babies probably experience the same sort of tiredness but the difference is they DO know it is going to end and it is a lot easier to explain when you oversleep at least twice a week. And I don't get sick pay or pto either. I get paid hourly so I either make it up or loose it.

Isn't the point of contacting your dr to figure this out? There isn't a one size fits all. It's not really up to strangers on a forum to tell you what you should and should not tolerate, no? It's kind of like telling people what they can eat or drink. Oh, I have a double latte after 4 everyday. You're just a wimp if you can't do that! Yeah, well I don't particularly like tossing and turning all night and then oversleeping the next day.

I feel like trying to quantify where the line of acceptable tolerance is just isn't possible. (Like when you say "can't drive".)


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I think it is definitely possible and does happen. The placebo effect. and people who are hypochondriac or tend to be that way.

For me I do alot of research and look at all the side effects and I don't get them. I have always been lucky and don't get many and usually get over the ones I do get. There are a couple I have learned to live with I would rather not have. they are the same two no matter what med. SSRI or SSNRI

Same doctor?

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I think some people can worry about all side effects but I don't think you can make yourself get them. Like give yourself a rash, glaucoma or crash your blood count.

The placebo effect is very powerful with meds.

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Exactly. The pamphlets are a only a guide (really a disclaimer) Side effects and how they impacf your treatment is something you discuss with your doctor. Plus its usually information gathered from participants in trials that last maybe 6 weeks. I remember when I took parnate, an MAOI, one of the common side effects was weight loss. I gained 35 pounds while on it. When I had a serious conversation with my pdoc about it, he said that lately he had been noticing that even though the literature notes weight loss as a side effect, in practice he found it caused weight gain more often. Interestingly, Weight gain isn't listed anywhere in write ups on Parnate. I think the same is the case with some SSRIs (probably because of that initial nausea some people have initially that subsides).