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Grand Poohbah
Member Since Jan 2013
Posts: 1,773
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#1
What kind of experiences have people had or know about concerning higher doses of Wellbutrin XL? I was at 300mg, which is the standard target dose. It worked for a while, but my depression worsened. I was bumped up to 450mg. I'm also taking the atypical stimulant Provigil at 200mg. You would think that these two highly activating agents would work, right?
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Elder
Member Since Feb 2014
Location: Michigan
Posts: 5,481
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#2
You would think. Maybe to much.
Is the provigal for depression or ADHD? __________________ The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman Major Depressive Disorder Anxiety Disorder with some paranoid delusions thrown in for fun. Recovering Alcoholic and Addict Possibly on low end of bi polar spectrum...trying to decide. Male, 50 Fetzima 80mg Lamictal 100mg Remeron 30mg for sleep Klonopin .5mg twice a day, cutting this back |
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Grand Poohbah
Member Since Jan 2013
Posts: 1,773
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#3
Depression. Extreme lack of energy and some daytime sleepiness. That has improved some. I took Provigil years ago for like 6 years as my primary anti-depressant. It took a little work to get my new shrink to prescribe it and get it approved but it is working.
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Account Suspended
Member Since Nov 2013
Location: San Deigo
Posts: 1,154
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#4
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Account Suspended
Member Since Feb 2014
Location: Pebble Beach
Posts: 96
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#5
I agree with vans, Provigil is a CNS psycho stimulant, not an anti-depressant. At the highest dose of Bupropion, if you still were depressed, I'd switch meds or add another anti-depressant.
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Grand Poohbah
Member Since Jan 2013
Posts: 1,773
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#6
I know Provigil is not an anti-depressant. I am started it for fatigue associated with depression. The fatigue was so serious that I was becoming despairing because I was unsure that I would be able to work a full day in an upcoming position. It was a last ditch effort to bring me up out of that. There are studies that have shown effectiveness for depression but it is not indicated for that. I did take it before for 6 years as really the main drug for depression and did okay on it. I think I may have taken Lamictal too. I am hoping the Wellbutrin kicks in soon so I can see. I've tried so many other anti-depressants and not really had much luck. Lexapro somewhat. I am somewhat nervous about taking these two together and the Wellbutrin at the maximum dose. I wouldn't want to do that very long, but if it pulls me out for now, maybe it is worth it.
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Member
Member Since Sep 2014
Location: Rochester
Posts: 428
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#7
I am on a constant script for bupropion, and it works pretty well, usually. But I do find it can agitate me and make me irritable too. I also find it does very little for severe depression, and nothing for anxiety. So I occasionally need the help of a 2nd AD.
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