[circles5]

Hi there,

I have to start taking Clomipramine soon, and i'm very anxious about doing so.
i'll be starting on 10mg in the next few days.. on going up from there..

I was wandering how it makes you feel in comparison to SSRIs..
It's a tricylic, so i expect it to be quite different.
I'm particularily worried as i've had bad experiences with anti-depressants in general...
I really don't want to take any more, but to qualify for residential treatment i have to take either
a) an SSRI at maximum dosage augmented with an anti-pychotic
b) clomipramine at the maximum tolerated dose (150mg) {i believe it may go even higher according to ocd-uk}

I've had really bad experiences with SSRIs, going onto them and coming off them has always been particularily difficult; but i've also felt numb and empty whilst 'stabalised' on them with very little benefit towards my anxiety.
I also tried Mirtazapine, which actually worked well on my depression for a couple of months before it stopped working,, although it gave me terrible nightmares.
---

I'm going in and out of depression at the moment, my OCD is rampant..

What should i expect from clomimpramine?
Will it feel 'heavier',,,,, more 'dirty'.... sedating or confusing?
I know everyone has different subjective effects... but i really don't have a clue what's going to happen when i take it..
For instance: when i started taking Sertraline: for the first couple weeks i'd not sleep for 72hours in a row...
Mirtazapine i'd only be awake for 4 hours a day.

I'm very apprehensive as to just what is going to happen this time.

thanks for any views on this,
regards,
C

[circles5]

right, so i'm going to be starting today..
wish me luck.

[Angelique67]

Originally Posted by circles5

right, so i'm going to be starting today..
wish me luck.

Good luck, circles! I hope it will help without side effects!

[*Laurie*]

Good luck - and let us know how the Clomipramine works for you, Circles.

[LonesomeTonight]

I think the tricyclics work on serotonin, norepinephrine, and dopamine, right? If so, that's basically like what I'm starting on now, with Zoloft (SSRI) and Wellbutrin (works on norepinephrine and dopamine). I was on Cymbalta (SNRI) and then Cymbalta and Wellbutrin, but had some Cymbalta side effects.

I'm on fairly low doses, but so far this combo is working OK for me. I've heard the tricyclics are very effective--hope it works for you!

I took clomipramine 100 mg for three months or so. It didn't do anything for me, but I didn't have any side effects either.