[xRavenx]

So I'm back on the regular, immediate release of Lamictal.

When I was on immediate release last time, I was on 300 mg (divided doses though AM and PM). Now, I'm on 400 mg (200 AM, 200 PM). Most people seem to be on nothing higher than 300 mg, except in rare circumstances. My pdoc is not certain if I will see a difference or not on 400 mg, but I am hoping I will benefit since I love how Lamictal has no side effects for me, but 200 mg was not enough to stabilize me (even with an AP and benzo).

Has anyone here noticed that 400 mg Lamotrigine has been more effective than 200 or 300 mg?? I'm just curious to hear about personal experiences since once I remember reading that there's not much of a clinical benefit moving past 200mg daily.

[usehername]

I've only ever been on 300mg + AP & benzos. Then we moved to Depakote because it wasn't working.

Originally Posted by xRavenx

I'm just curious to hear about personal experiences since once I remember reading that there's not much of a clinical benefit moving past 200mg daily.

I'm working my way up to 400mg. I'm at 350 right now.

For me personally, I saw a great improvement going from 200 to 300. I mean, I used to be extremely aggressive and angry all the time. Then the anger and aggression subsided once I reached 300.

So I do think there can be a great clinical benefit depending on the person. It kinda depends on your symptoms, though.

The main reason I'm upping my dose *now* is that I had a recent hypomanic episode and we are trying to prevent those from occurring the best we can.

Sorry I can't answer your main question, though.

[usehername]

It DEFINITELY is very individual... Depakote has been the only thing that could slow me down and I still need the benzos. I was even on 800mg of seroquel at one point.