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#1
Apr 30, 2025, 11:27 PM
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I have learned today of a whole new class of antipsychotics that do not act on dopamine receptors.
Cobenfy was approved in 2024 by the FDA. FDA Approves Drug with New Mechanism of Action for Treatment of Schizophrenia | FDA Other drugs in this class are in development. NeuRA | Understanding Cobenfy: A conversation with NeuRA’s Dr Tertia…. For now, the approval is for Schizophrenia, but often antipsychotics are approved for Schizophrenia first, for Bipolar second, and as an adjunct treatment for MDD third.
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 10 mg Naltrexone 75 mg Gabapentin 1500 mg+Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity BMI ~ 38 |
 Crazy Hitch, shadow2000
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#2
Apr 30, 2025, 11:31 PM
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Cobenfy is not for anyone with liver or urinary issues, though, even when these issues are mild.
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 10 mg Naltrexone 75 mg Gabapentin 1500 mg+Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity BMI ~ 38 |
| Crazy Hitch, shadow2000
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#3
May 01, 2025, 12:33 AM
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Quote:
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Qui Cantat Bis Orat ingrezza 80 mg Propranolol 40 mg Benztropine 1 mg Vraylar 3 mg Gabapentin 300 mg Klonopin 1 mg 2x daily Mania Sept/Oct 2024 Mania (July/August 2024) Mania (December 2023) Mixed episode/Hypomania (September 2023) Depression, Anxiety and Intrusive thoughts (September 2021) Depression & Psychosis (July/August 2021) |
 Brentus, Tart Cherry Jam
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#4
May 01, 2025, 06:53 AM
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I was disappointed to see the US FDA pass on approving psychedelics as a treatment option. Psilocybin, MDMA, and Ketamine have shown promise in treating depression. While Psilocybin and MDMA are approved for treatment in Australia, only Ketamine is being used off label by clinics in the US. Mental health accounts for an estimated 30% of US health care costs, so anything that might disturb the marketplace has to be very carefully considered. One problem with psilocybin is that the mushrooms can be grown in a tub in a warm dark place. While not as easy as growing tomatoes, it is just as rewarding. All the necessary ingredients are available on line and micro-dosing has become a trend in silicon valley.
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| bizi, Brentus
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| bizi, Brentus
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#5
May 01, 2025, 10:47 AM
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Where was that figure 30% of US healthcare spent on mental health determined?
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 10 mg Naltrexone 75 mg Gabapentin 1500 mg+Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity BMI ~ 38 |
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#6
May 05, 2025, 10:39 AM
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It would appear I pulled the 30% figure out of thin air. Googling, I did find sources that suggested mental health costs were 5% of total health expenditures, and one source
even said that mental health costs were 30% higher than expected. lol |
| Brentus
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| Brentus
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#7
May 05, 2025, 06:53 PM
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Oh, I see. That makes much more sense. Thank you
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 10 mg Naltrexone 75 mg Gabapentin 1500 mg+Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity BMI ~ 38 |
| bizi, forestx5
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