rebound symtoms

ONe of my diagnoses is dysthymia. For this I've been prescribed Zoloft with Abilify.

A couple of weeks ago I forgot to take my Zoloft on one night, remembered the next, and, again forgot on the night after that. The end result was a quick return of the sadness and feeling of hopelessness.

I though Zoloft builds up in your system. Unless I process it out quicker than most.

Anyone else have a similar issue with rebound symptoms coming on so quickly?
Makes me concerned that if ever I can't get my meds that I'll be a basket case in no time flat.

Did the sadness come a few days later, or the same day? I hear a lot of these meds won't affect you if you forget until a while later.

It seemed to come on within 24 hours or so. That's what scared me was that it came on so quick. Makes me nervous about situations where I might not be able to get my medication when needed. Basically I have a 24 hour window of opportunity before the sadness and hopelessness set in. I don't know if it's these meds in particular or if it's me.

Yes, I had the same experience on citalapram. I am pretty sensitive to meds period. Any sort of reduction I do has to be tiny and slow so missing a day can send me to tears depending where my mental and physical health is. I am very uncomfortable with this. I like to travel. What if there was a problem and I couldn't get a hold of the med? And the idea of being on it for a lifetime is an even worse prospect. I'm ok with it as a tool to get back on track and learn self care but then I want off.

I'm glad you posted because I tried to explain my concerns to a few people and they gave me such a hard time about it. I am not around those people any more but I still feel it was shaming. I never understood their reaction either.

I tend to have lots of problems regulating meds. Even skipping one dose can cause problems. Over a period of many years my meds doc has finally figured out that any changes require tapering off one med while tapering up on the new one. Can you guess how hard it is to cut some very tiny pills into 4 pieces when there is not a lower dosage available? After 2 visits to hospital for getting meds regulated I am very careful about not forgetting to take them or calling doc to see if I should change time to take or forget till next scheduled time. Most times with my history he will tell me to take right away and how to go about getting back on schedule. Big PITA but beats another trip to hospital.

Call your doc to see what they suggest since you are noticing problems with only a single missed dose.

I'm seeing him today and will ask about this.

I usually space out the three meds that I'm on because I've learned that taking them too close together causes either upset stomach, anxiety/racing heart beat, or dizziness. Funny because when I look up the combination of meds I'm on, there are no noted drug interactions but I know from experience that I can't take all three at or around the same time. So a missed dose becomes a tricky issue to deal with.

I don't know why anyone would scoff at another person's concerns regarding their medication. While I understand that lay people or people without MH issues have a hard time putting themselves in our shoes, it's not so hard to understand. Would you scoff at a diabetic who expresses concern over the possibility of not getting access to insulin? Sorry for the mini rant, it's just that I've come to understand my diagnosis's as being a true illness, not a character flaw. My brain isn't operating they way a brain should and so I have to take medication. No different than the diabetic with a faulty pancreas.

Just got back from the pdoc.

He and I looked up the half life time of zoloft and it is 26 hours. Some people metabolize the drug quicker than others which may shorten the duration to 23 or 24 hours.