Adderall XR - works best the first day, makes me more anxious?

Adderall XR seems to help a LOT the first day I take it after a break. I'll be very focused, very positive, a little aggressive (maybe from cockiness), etc. The effectiveness seems to wear off after the first day.

Also, I have anxiety as a major symptom. No matter what I do, I'll feel like I should be doing something else. Novel things feel good. I've been taking St. John's Wort for that since August, and I believe it helps a ton. I haven't taken Adderall since before then. Should I try it again now? Adderall seemed to make the anxiety worse -- it didn't make me cheerful. Caffeine seems to help things though.

Anyway, so should I try Adderall again? Or should I try Focalin or something?

Thanks
Sean

Do not take St Johns and adderall at the same time, that is a major interaction problem. After a day or 2 your body becomes more adjusted to the euphoric aspects of it and that is what you were describing.

Humm, well that's too bad. I had someone else tell me they wouldn't interact. Can you describe why I shouldn't do it?

If I take something, I'll need it to address my anxiety/racing thoughts. Can you recommend something?

Thanks,
Sean

St J is a monamine oxidase inhibitor in part, and amphetamines cause massive release of such monoamines that then cannot be metabolized thus the increased anxiety etc...

Well when I was taking Adderall XR, I wasn't on SJW. I've never taken them both together.

I've taken L-Tyrosine before along with SJW. Would something like L-Tyrosine or DLPA be goodinstead of Adderall XR?

Thanks,
Sean