[pearlys]

Hi, i have severe sleeping problems which in the past were treated with mirtazapine. For some reason i quit the mirta (i thought my fatigue was because of the mirta but i think i exhausted myself during hypomanic episode). After almost one year of depression, hospitalisation, unable to work, i am on lexapro (escitalopram) and for sleep in take quitiapine (seroquel) 25mg. but the seroquel just works about 6 hours and i wake up. i still have some mirtazapine (remeron) which even in 15 mg dose helps me sleep very well. I cannot reach my pdoc at the moment but would it be safe to combine the 5mg of escitalopram with 15mg mirtazapine. for the time being until the escitalopram starts to work and hopefully relieves my anxiety, stress and depression and hopefully i sleep well again without sleeping medication.

[Ruftin]

(((pearlys))) Please continue reaching out to your p-doc for advice with your meds. Getting advice from someone without a medical degree would be unsafe. I hope you sleep well soon. Best wishes!!!

[pearlys]

Tried it for 2 nights, just a half (so 7.5mg mirtazapine) but i get restless legs syndrome. I continue my quetiapine but that also gives me restless legs. could it be the escitalopram giving me RLS?

[pearlys]

Had contact with my pdoc today; 7.5mg mirtazapine or quetiapine for sleep is fine but of course she says if it gives me restless legs than max twice a week a benzo would be an option or promethazine which i still have. however promethazine gives me a massive hangover which makes me get out of bed very hard. but that was already very hard, couldnt get out of bed anyway even without any medication.

[pinkflower17]

Originally Posted by pearlys

Tried it for 2 nights, just a half (so 7.5mg mirtazapine) but i get restless legs syndrome. I continue my quetiapine but that also gives me restless legs. could it be the escitalopram giving me RLS?

Lexapro and celexa have been known to cause restless leg syndrome. There's several case reports out there regarding this. I would almost bet it's the Lexapro and not the Seroquel or remeron causing the RLS. Maybe ask for a different SSRI?

[pearlys]

Well, the lexapro in itsel doesnt cause restless legs, as opposed to mirtazapine when i was on it (half an hour after taking it i got rls). but the combination does. so i suppose it is still the mirtazapine cuz i had it before. however i didnt have it on seroquel. im not taking mirtazapine or seroquel now cuz of that. i use promethazine but that works very slow and doesnt knock me out however once i am asleep i sleep well on it. i dont wanna switch to quick to another med. it took me a year to decide to go on an anti depressant and i slowly recovered without. but lately my depression got worse and that was the moment i asked my pdoc. she adviced me lexapro because of its low side effects profile. i didnt want a stimulating anti depressant like wellbutrin because i already have severe sleeping problems and i dont want to worsen that. besides i dont like to get "artificial energy" as i call it. 1.5 years ago on paxil i went hypomanic.

good luck with it. im on remeron and Seroquel too and I've found that both have helped slowly lift my depression. also they knock me out at night and I sleep like a baby... a small miracle for a chronic insomniac.

[pinkflower17]

I hope the Phenergan continues to work for you. I'm a total chronic insomniac too and the only meds that have ever really worked for my insomnia are Seroquel and trazodone. I don't know if you've ever tried trazodone, but maybe something to discuss with your dr if the promethazine stops working...

[pinkflower17]

Originally Posted by pearlys

Hi, i have severe sleeping problems which in the past were treated with mirtazapine. For some reason i quit the mirta (i thought my fatigue was because of the mirta but i think i exhausted myself during hypomanic episode). After almost one year of depression, hospitalisation, unable to work, i am on lexapro (escitalopram) and for sleep in take quitiapine (seroquel) 25mg. but the seroquel just works about 6 hours and i wake up. i still have some mirtazapine (remeron) which even in 15 mg dose helps me sleep very well. I cannot reach my pdoc at the moment but would it be safe to combine the 5mg of escitalopram with 15mg mirtazapine. for the time being until the escitalopram starts to work and hopefully relieves my anxiety, stress and depression and hopefully i sleep well again without sleeping medication.

I also wanted to mention; have you ever been checked for anemia? Anemia is a common cause of restless leg syndrome as well as fatigue and can be caused by a lot of meds among other things (lack of adequate nutrition, heavy menstrual bleeding etc). It's something that can be easily checked for and treated. Just an idea.

[pearlys]

Originally Posted by 8888an8888

good luck with it. im on remeron and Seroquel too and I've found that both have helped slowly lift my depression. also they knock me out at night and I sleep like a baby... a small miracle for a chronic insomniac.

im on lexapro/escitalopram. but before i started lexapro i used seroquel to sleep. seroquel didnt do anything for my depression.

Originally Posted by pinkflower17

I also wanted to mention; have you ever been checked for anemia? Anemia is a common cause of restless leg syndrome as well as fatigue and can be caused by a lot of meds among other things (lack of adequate nutrition, heavy menstrual bleeding etc). It's something that can be easily checked for and treated. Just an idea.

Yes everything was fine. last time i had a small lack of vitamine d, i suppose because i stayed inside 24/7. i take multivitamin/mineral supplement and extra vitamine d.

[pearlys]

i suppose the fatigue is from the depression. when i wake up in the morning, i have absolutely no motivation to get up, no reason to live anymore.