[SecretGarden]

I am taking seroquil now at night that does let me sleep though I do feel a bit groggy in the day (seroquil vs depression??) I am about to up my dose of lexapro from 10 to 20 and wonder if I am a working girl... when is the best time to take the meds. Pdoc is leaving it up to me though I would like to know when.

Is there a significant grog increase with moving from 10 to 20? I take 10 at night.

[sunrise]

Hi SG,
Have you noticed any difference in taking lexapro 10 mg at night vs. during the day? I was recently talking to my PCP about the best time to take Lexapro, as I may start on that. She said that once you are established on it, it shouldn't matter, because of its long half life. It builds up to a certain amount in your system and stays fairly constant. That's why you only need to take it once a day. But I think it is always a good rule of thumb to take the med at the same time each day. I don't know when is the best time for seroquil or whether it has a short or long half life. Good luck!

sunny

[SecretGarden]

I used to take it (before I lapsed) in the day and now I take it at night. It seems to work either way. The thing is the seroquil (I take for sleep, etc.. ) and I do not know if the grogginess I am experiencing is the seroquil or this lovely depression.

I hear that it will take another 7-14 days for the upgrade to kick in. Just have to be optimistic.

It would be great to take it all at one time. I have a call in to pdoc but think he will not respond. We shall see.

I have never taken more than 10 mg.

It sedates me but hear it does the opposite for others.

Thanks Sunny.

[debbie_tabor]

I was taking seroquel, citalopram and wellbutrin, and needing 12 hours sleep a night, and finding it very difficult to wake up and get up. When I came off the meds, I could wake up much easier (just lacked the motivation to get up!). I thought seroquel was great for getting to sleep, but I think it might have contributed to the fatigue.

[SecretGarden]

I do not doubt that. I think I am living it.....

[debbie_tabor]

Yeah, I'm tippy-toeing a bit given my meds combo, but I had the same question about depression/meds causing the fatigue, and I am now convinced it was the meds.

[SecretGarden]

Increased Lexapro last night to 15 and did not sleep much last night. This could be a long day. Not sure how to do this....... tired on many levels. So need the meds to sleep... but they grog me.

[debbie_tabor]

Sorry to be obvious but best to discuss with your pdoc when you get a chance.

[SecretGarden]

4:00 a.m..... I will. Also, now nervous. Good in evenings. Rough in days.