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#1
Mar 10, 2005, 02:24 PM
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My doctor swiched me from Celexa to Lexapro due to sexual side effects. Anyone heard anything about this? Also what is the weight gane issue? More than Celexa or More o Lexapro??
Thanks.
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#2
Mar 10, 2005, 06:49 PM
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The Celexa molecule (chemical name citralopram) comes in a right-handed and left-handed version just as gloves are handed. They figured out that only the left-handed version was useful for depression and separated it from the right-handed version (which only causes side effects). The left-handed version by itself is called Lexapro (escitralapram - es standing for left) and is exactly half the dose of Celexa because Celexa is 50% left and right-handed. Leaving out the right-handed molecules is thought to eliminate some side effects. I don't know if this means less sexual side effects with Lexapro though, the sexual side effects are related to serotonin. There is no long-term evidence of weight gain with either, as neither stimulate the H1 histamine receptors in the brain responsible for increased appetite.
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