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Old Nov 15, 2006, 06:51 PM
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babs92 babs92 is offline
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My doc has just upped by Zoloft medication from 50mg to 100mg five days ago and am feeling EXTREMELY anxious in the daytime and by early evening am exhausted and tired out...........could this be the change in dose? Plus! I am still feeling very very depressed, although initially was lifted out of the depression (maybe it was psychological) I have come crashing down again. Any thoughts?

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  #2  
Old Nov 15, 2006, 07:04 PM
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biplol biplol is offline
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Oh hon, i hope I could help you, but I'm off meds, so i ahve no idea.
Talk to your Pdoc about it and hang in there!
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Old Nov 16, 2006, 05:52 PM
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babs92 babs92 is offline
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Thanks Biplol I am just about hanging in there, its difficult but I am trying......best wishes to you.
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Old Nov 18, 2006, 07:03 PM
maureen maureen is offline
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Zoloft increase However, Babs, I believe that Zoloft is similar to Prozac and Paxil which are actually raising your Dopamine level artificially without any chance for re-uptake ( Dopamine replenishings itself naturally). Of course, I am NOT a pdoc, but your anxiety during the day could be like your on a amphetamine and at night you are coming down from it.
Regarding that you still feel depressed (recently people on prozac and paxil have told me this) that a tolerance is built up although I know your pdoc has increased your dosage.
Another possiblilty is did you for a day or two go off the Zoloft; that as we all know will cause a crash (like a cocaine addict trying to withdraw.) Additionally, I'm surprised that you are on Zoloft; Bi-polars are not to be treated normally with anti-depessants ((perhaps Wellbutrin and other exceptions if the anti-manics aren't helping the depression ) because they can cause us to go into a manic episode. Although, yes, Zoloft is given for anxiety but not to make you have more of it. Lithium is an anti-manic and I've been told by my pdocs when I go off of it in the Spring (high time for depression and suicide, especially May) that the Lithium will help somewhat with the depression. I have a hard time with that. Maureen
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Old Nov 18, 2006, 07:26 PM
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babs92 babs92 is offline
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Hi Maureen, that's an interesting reply. I have BP2 (hypomania with mixed states) and have been on Depakote since May - started at 750mg a day increased to 1000mg a few months ago. When I got the diagnosis doc immediately changed Effexor (she thought it was a trigger for the mania) and switched me to Sertraline (Zoloft) think they call it Sertraline here in the UK!? I hope I have that right.

I felt a bit manic last couple of days on higher dose coupled with anxiety and now my head feels sooooooo foggy in the mornings and I feel REALLY tired and sort of numb. I didnt stop taking the Zoloft at any time.

I have heard much about Wellbutrin - what is it exactly?

Sounds like you have similar symptoms to Seasonal Affective Disorder - I have this also - horrible.....
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